A systematic review and meta-analysis of 15 studies identified 55 long-term effects of COVID-19, with 80% of infected patients experiencing at least one long-term symptom. The most common symptoms were fatigue (58%), headache (44%), attention disorder (27%), hair loss (25%), and dyspnea (24%). Long-term effects included physical symptoms, neurological issues, and abnormal laboratory parameters. The study highlights the need for multidisciplinary approaches to address long-term care. The prevalence of long-term effects was estimated using a random-effects model, with 47,910 patients included. The study found that long-term effects can occur in both severe and mild cases, and factors such as age, gender, and underlying health conditions may influence the risk. The research emphasizes the importance of further studies to understand the long-term impacts of COVID-19 and develop effective management strategies. The findings suggest that long-term effects of COVID-19 are significant and require ongoing attention and research.A systematic review and meta-analysis of 15 studies identified 55 long-term effects of COVID-19, with 80% of infected patients experiencing at least one long-term symptom. The most common symptoms were fatigue (58%), headache (44%), attention disorder (27%), hair loss (25%), and dyspnea (24%). Long-term effects included physical symptoms, neurological issues, and abnormal laboratory parameters. The study highlights the need for multidisciplinary approaches to address long-term care. The prevalence of long-term effects was estimated using a random-effects model, with 47,910 patients included. The study found that long-term effects can occur in both severe and mild cases, and factors such as age, gender, and underlying health conditions may influence the risk. The research emphasizes the importance of further studies to understand the long-term impacts of COVID-19 and develop effective management strategies. The findings suggest that long-term effects of COVID-19 are significant and require ongoing attention and research.