31 May 2024 | Chinedu O. Egwu, Chinyere Aloke, Kenneth T. Onwe, Chukwunalu Igbudu Umoke, Joseph Nwafor, Robert A. Eyo, Jennifer Adeeze Chukwu, Godswill O. Ufebe, Jennifer Ladokun, David Tersoo Audu, Anthony O. Agwu, David Chukwu Obasi, Chukwuemeka O. Okoro
The article "Nanomaterials in Drug Delivery: Strengths and Opportunities in Medicine" by Chinedu O. Egwu et al. discusses the potential of nanotechnology in improving drug delivery systems to enhance therapeutic outcomes. The authors highlight the challenges faced in conventional drug delivery methods, such as drug resistance, toxicity, and reduced efficacy, and emphasize the need for innovative approaches. Nanotechnology, with its ability to manipulate materials at the nanoscale, offers solutions by enhancing drug stability, solubility, and targeted delivery. The article reviews various types of nanoparticles used in drug delivery, including liposomes, micelles, dendritic macromolecules, quantum dots, carbon nanotubes, and metal-based nanoparticles. These nanoparticles are discussed in terms of their properties, advantages, and limitations. The authors also explore the applications of nanotechnology in treating resistant infectious diseases, cancer, cardiovascular diseases, and gene therapy. Despite the promising results, the article identifies challenges such as toxicity, biocompatibility, cost, regulatory hurdles, and poor biodistribution. To address these challenges, the authors propose solutions, including regulatory streamlining, increased research funding, and innovative design strategies. The article concludes by emphasizing the importance of translating nanomedicine research into clinical practice to revolutionize treatment strategies and improve patient outcomes.The article "Nanomaterials in Drug Delivery: Strengths and Opportunities in Medicine" by Chinedu O. Egwu et al. discusses the potential of nanotechnology in improving drug delivery systems to enhance therapeutic outcomes. The authors highlight the challenges faced in conventional drug delivery methods, such as drug resistance, toxicity, and reduced efficacy, and emphasize the need for innovative approaches. Nanotechnology, with its ability to manipulate materials at the nanoscale, offers solutions by enhancing drug stability, solubility, and targeted delivery. The article reviews various types of nanoparticles used in drug delivery, including liposomes, micelles, dendritic macromolecules, quantum dots, carbon nanotubes, and metal-based nanoparticles. These nanoparticles are discussed in terms of their properties, advantages, and limitations. The authors also explore the applications of nanotechnology in treating resistant infectious diseases, cancer, cardiovascular diseases, and gene therapy. Despite the promising results, the article identifies challenges such as toxicity, biocompatibility, cost, regulatory hurdles, and poor biodistribution. To address these challenges, the authors propose solutions, including regulatory streamlining, increased research funding, and innovative design strategies. The article concludes by emphasizing the importance of translating nanomedicine research into clinical practice to revolutionize treatment strategies and improve patient outcomes.