The article reviews the application of nanotechnology in tissue engineering, focusing on the design of biomimetic scaffolds that mimic the extracellular matrix (ECM) to enhance tissue organization and function. It discusses the importance of nanostructures in promoting cellular processes such as morphogenesis, differentiation, proliferation, adhesion, and migration. The review highlights the use of nanofabrication techniques like electrospinning and molecular self-assembly to create scaffolds with specific nanostructures, and their impact on cell behavior. It also explores the incorporation of nanostructures to address limitations of traditional scaffolds, such as mechanical properties and electrical conductivity. Additionally, the article examines the use of nanodevices for triggering processes in tissue development and monitoring tissue behavior post-engineering. Finally, it discusses the challenges and future prospects of nanotechnology in tissue engineering, emphasizing the need for further research on biocompatibility and the development of advanced nanocomposite scaffolds for complex tissue engineering applications.The article reviews the application of nanotechnology in tissue engineering, focusing on the design of biomimetic scaffolds that mimic the extracellular matrix (ECM) to enhance tissue organization and function. It discusses the importance of nanostructures in promoting cellular processes such as morphogenesis, differentiation, proliferation, adhesion, and migration. The review highlights the use of nanofabrication techniques like electrospinning and molecular self-assembly to create scaffolds with specific nanostructures, and their impact on cell behavior. It also explores the incorporation of nanostructures to address limitations of traditional scaffolds, such as mechanical properties and electrical conductivity. Additionally, the article examines the use of nanodevices for triggering processes in tissue development and monitoring tissue behavior post-engineering. Finally, it discusses the challenges and future prospects of nanotechnology in tissue engineering, emphasizing the need for further research on biocompatibility and the development of advanced nanocomposite scaffolds for complex tissue engineering applications.