The article reviews the role of small-molecule hormones in plant immunity, highlighting their cross-communication and regulatory roles in the plant's defense signaling network. Phytohormones, such as salicylic acid (SA), jasmonic acid (JA), and ethylene (ET), play pivotal roles in regulating plant responses to pathogens. The article discusses how these hormones interact to fine-tune the plant's immune response, with SA, JA, and ET serving as primary signals in local and systemic defense signaling. It also explores the crosstalk between these hormone pathways, including antagonistic and synergistic interactions, and how pathogens can manipulate these networks to their advantage. The review emphasizes the importance of understanding the complex interactions between hormone signaling pathways and their implications for plant defense strategies against various pathogens.The article reviews the role of small-molecule hormones in plant immunity, highlighting their cross-communication and regulatory roles in the plant's defense signaling network. Phytohormones, such as salicylic acid (SA), jasmonic acid (JA), and ethylene (ET), play pivotal roles in regulating plant responses to pathogens. The article discusses how these hormones interact to fine-tune the plant's immune response, with SA, JA, and ET serving as primary signals in local and systemic defense signaling. It also explores the crosstalk between these hormone pathways, including antagonistic and synergistic interactions, and how pathogens can manipulate these networks to their advantage. The review emphasizes the importance of understanding the complex interactions between hormone signaling pathways and their implications for plant defense strategies against various pathogens.