This review article discusses neurological complications following third molar (M3) extraction surgery. The study aimed to explore postoperative neurological complications in third molar extractive surgery. A systematic review of 2,250 articles was conducted using PRISMA protocols, resulting in 11 relevant articles. The review highlights that temporary loss of sensation is a common complication, often caused by mild compression or irritation of the mandibular nerve (IAN), which typically resolves within weeks or months. However, severe cases may result in permanent loss of sensation, indicating significant nerve damage. The IAN is particularly susceptible to injury during M3 extraction, with symptoms including paresthesia, anesthesia, and dysesthesia. The lingual nerve (LN) is also at risk, with damage leading to sensory loss in the tongue and floor of the mouth. The study emphasizes the importance of preoperative radiographic evaluation, such as CT scans, to predict the risk of nerve damage. Postoperative management includes treatments like low-level laser therapy, pain management, and physical therapy. The review also discusses various risk factors for nerve injury, including the degree of tooth impaction, surgical technique, and patient characteristics. The study concludes that accurate preoperative evaluation, modern surgical techniques, and effective postoperative management can help minimize risks and improve outcomes for patients undergoing M3 extraction. The review highlights the importance of timely diagnosis and treatment of nerve injuries to prevent long-term complications and improve patients' quality of life.This review article discusses neurological complications following third molar (M3) extraction surgery. The study aimed to explore postoperative neurological complications in third molar extractive surgery. A systematic review of 2,250 articles was conducted using PRISMA protocols, resulting in 11 relevant articles. The review highlights that temporary loss of sensation is a common complication, often caused by mild compression or irritation of the mandibular nerve (IAN), which typically resolves within weeks or months. However, severe cases may result in permanent loss of sensation, indicating significant nerve damage. The IAN is particularly susceptible to injury during M3 extraction, with symptoms including paresthesia, anesthesia, and dysesthesia. The lingual nerve (LN) is also at risk, with damage leading to sensory loss in the tongue and floor of the mouth. The study emphasizes the importance of preoperative radiographic evaluation, such as CT scans, to predict the risk of nerve damage. Postoperative management includes treatments like low-level laser therapy, pain management, and physical therapy. The review also discusses various risk factors for nerve injury, including the degree of tooth impaction, surgical technique, and patient characteristics. The study concludes that accurate preoperative evaluation, modern surgical techniques, and effective postoperative management can help minimize risks and improve outcomes for patients undergoing M3 extraction. The review highlights the importance of timely diagnosis and treatment of nerve injuries to prevent long-term complications and improve patients' quality of life.