Since January 2020, Elsevier has provided free English and Mandarin resources on COVID-19. The company grants permission for free access to its research in PubMed Central and other repositories. The article discusses neurological manifestations of SARS-CoV-2, including encephalopathy, encephalitis, Guillain-Barré syndrome, and acute cerebrovascular disease. Over 900 patients have been reported, with neurological symptoms ranging from encephalopathy to stroke. The article highlights the need for careful studies to define the burden of neurological disease caused by SARS-CoV-2. It also discusses the mechanisms of infection and inflammation in the central and peripheral nervous systems, as well as the role of coagulopathy in cerebrovascular disease. The article emphasizes the importance of distinguishing between viral and non-viral causes of neurological disease and the need for standardized case definitions. It also notes the potential for long-term neurological sequelae and the need for healthcare planners to prepare for the increasing number of neurological patients. The article concludes that further research is needed to determine the causal relationship between SARS-CoV-2 and neurological disease.Since January 2020, Elsevier has provided free English and Mandarin resources on COVID-19. The company grants permission for free access to its research in PubMed Central and other repositories. The article discusses neurological manifestations of SARS-CoV-2, including encephalopathy, encephalitis, Guillain-Barré syndrome, and acute cerebrovascular disease. Over 900 patients have been reported, with neurological symptoms ranging from encephalopathy to stroke. The article highlights the need for careful studies to define the burden of neurological disease caused by SARS-CoV-2. It also discusses the mechanisms of infection and inflammation in the central and peripheral nervous systems, as well as the role of coagulopathy in cerebrovascular disease. The article emphasizes the importance of distinguishing between viral and non-viral causes of neurological disease and the need for standardized case definitions. It also notes the potential for long-term neurological sequelae and the need for healthcare planners to prepare for the increasing number of neurological patients. The article concludes that further research is needed to determine the causal relationship between SARS-CoV-2 and neurological disease.