This review article explores next-generation materials for space electronics, emphasizing their potential to enhance performance, reliability, and resilience in the harsh space environment. Space electronics are critical for modern space missions, enabling communication, navigation, remote sensing, and scientific exploration. However, extreme conditions such as temperature fluctuations, radiation exposure, and mechanical stresses pose significant challenges for electronic components. The review outlines the fundamental requirements for space electronics materials, including extreme temperature resistance, radiation shielding, mechanical strength, and thermal conductivity. It surveys current state-of-the-art materials such as silicon-based materials, compound semiconductors, polymers, ceramics, and composites, highlighting their strengths and limitations. Emerging materials like 2D materials, organic electronics, quantum materials, and metamaterials are also discussed, as they hold promise for revolutionizing space electronics. Implementation strategies are proposed, considering factors such as integration with existing systems, scalability, cost-effectiveness, environmental impact, and regulatory compliance. The review concludes by summarizing key findings, emphasizing the potential implications for the future of space electronics, and offering recommendations for further research and development. The article underscores the importance of advancing materials science for space electronics to support future space exploration and scientific discovery.This review article explores next-generation materials for space electronics, emphasizing their potential to enhance performance, reliability, and resilience in the harsh space environment. Space electronics are critical for modern space missions, enabling communication, navigation, remote sensing, and scientific exploration. However, extreme conditions such as temperature fluctuations, radiation exposure, and mechanical stresses pose significant challenges for electronic components. The review outlines the fundamental requirements for space electronics materials, including extreme temperature resistance, radiation shielding, mechanical strength, and thermal conductivity. It surveys current state-of-the-art materials such as silicon-based materials, compound semiconductors, polymers, ceramics, and composites, highlighting their strengths and limitations. Emerging materials like 2D materials, organic electronics, quantum materials, and metamaterials are also discussed, as they hold promise for revolutionizing space electronics. Implementation strategies are proposed, considering factors such as integration with existing systems, scalability, cost-effectiveness, environmental impact, and regulatory compliance. The review concludes by summarizing key findings, emphasizing the potential implications for the future of space electronics, and offering recommendations for further research and development. The article underscores the importance of advancing materials science for space electronics to support future space exploration and scientific discovery.