The study reports a method to enhance the efficiency of hybrid perovskite solar cells (PHJ) by growing large-aspect-ratio grains on non-wetting hole transport layers (HTLs). The non-wetting HTLs, such as c-OTPD, PTAA, and PCDTBT, increase nucleus spacing and facilitate grain boundary migration, leading to reduced grain boundary area and improved crystallinity. This results in a significant reduction in charge recombination, similar to that in single-crystal perovskite films. The use of high-work-function HTLs, particularly c-OTPD, further enhances device performance, achieving a stabilized device efficiency of 18.3% under 1 sun illumination. The mechanism involves suppressing heterogeneous nucleation and reducing the drag force on grain boundaries, which improves the mobility and passivation of charge traps. The study also demonstrates the potential of these HTLs in other optoelectronic devices due to their enhanced performance and stability.The study reports a method to enhance the efficiency of hybrid perovskite solar cells (PHJ) by growing large-aspect-ratio grains on non-wetting hole transport layers (HTLs). The non-wetting HTLs, such as c-OTPD, PTAA, and PCDTBT, increase nucleus spacing and facilitate grain boundary migration, leading to reduced grain boundary area and improved crystallinity. This results in a significant reduction in charge recombination, similar to that in single-crystal perovskite films. The use of high-work-function HTLs, particularly c-OTPD, further enhances device performance, achieving a stabilized device efficiency of 18.3% under 1 sun illumination. The mechanism involves suppressing heterogeneous nucleation and reducing the drag force on grain boundaries, which improves the mobility and passivation of charge traps. The study also demonstrates the potential of these HTLs in other optoelectronic devices due to their enhanced performance and stability.