2017 | Mohammed S. Ellulu, Ismail Patimah, Huzwah Khaza'ai, Asmah Rahmat, Yehia Abed
Obesity is associated with chronic inflammation, which contributes to various diseases. Excess fat in adipose tissue releases inflammatory mediators like IL-6 and TNF-α, while reducing adiponectin, an anti-inflammatory hormone. This leads to a pro-inflammatory state and oxidative stress. IL-6 stimulates the liver to produce C-reactive protein (CRP), a marker of systemic inflammation. Obesity is linked to metabolic syndrome, which includes conditions like insulin resistance, diabetes, and cardiovascular diseases. Inflammation also contributes to non-cardiovascular diseases such as psoriasis, depression, and cancer. Adiponectin, a key anti-inflammatory marker, is reduced in obesity, increasing the risk of metabolic disorders and cardiovascular events. Managing obesity can reduce inflammation and improve health outcomes. IL-6 and CRP are important inflammatory markers, with IL-6 playing a role in CRP production. Obesity increases IL-6 and CRP levels, which are associated with cardiovascular and metabolic risks. Adiponectin levels are also reduced in obesity, further contributing to inflammation and disease. The link between obesity and inflammation involves complex interactions between adipose tissue, immune cells, and inflammatory mediators. Obesity increases the risk of cardiovascular diseases, diabetes, and other conditions through inflammatory mechanisms. Understanding these links is crucial for developing effective interventions to reduce the health risks associated with obesity.Obesity is associated with chronic inflammation, which contributes to various diseases. Excess fat in adipose tissue releases inflammatory mediators like IL-6 and TNF-α, while reducing adiponectin, an anti-inflammatory hormone. This leads to a pro-inflammatory state and oxidative stress. IL-6 stimulates the liver to produce C-reactive protein (CRP), a marker of systemic inflammation. Obesity is linked to metabolic syndrome, which includes conditions like insulin resistance, diabetes, and cardiovascular diseases. Inflammation also contributes to non-cardiovascular diseases such as psoriasis, depression, and cancer. Adiponectin, a key anti-inflammatory marker, is reduced in obesity, increasing the risk of metabolic disorders and cardiovascular events. Managing obesity can reduce inflammation and improve health outcomes. IL-6 and CRP are important inflammatory markers, with IL-6 playing a role in CRP production. Obesity increases IL-6 and CRP levels, which are associated with cardiovascular and metabolic risks. Adiponectin levels are also reduced in obesity, further contributing to inflammation and disease. The link between obesity and inflammation involves complex interactions between adipose tissue, immune cells, and inflammatory mediators. Obesity increases the risk of cardiovascular diseases, diabetes, and other conditions through inflammatory mechanisms. Understanding these links is crucial for developing effective interventions to reduce the health risks associated with obesity.