Objectively measured physical capability levels and mortality: systematic review and meta-analysis

Objectively measured physical capability levels and mortality: systematic review and meta-analysis

2010 | Rachel Cooper, MRC career development fellow Diana Kuh, professor of life course epidemiology and MRC unit director Rebecca Hardy, MRC programme leader, Mortality Review Group on behalf of the FALCon and HALCyon study teams
This systematic review and meta-analysis examines the associations between objective measures of physical capability (grip strength, walking speed, chair rising, and standing balance times) and mortality in community-dwelling populations. The review included published and unpublished data from observational studies, with a focus on all-cause mortality. The results consistently showed that individuals who performed poorly in these tests had a higher risk of mortality. For example, the summary hazard ratio for mortality comparing the weakest with the strongest quarter of grip strength was 1.67 (95% CI 1.45 to 1.93), and for walking speed, it was 2.87 (95% CI 2.22 to 3.72). The associations were found in both older and younger populations, although most studies were conducted in older adults (average age over 70 years). The review highlights the value of objective measures of physical capability as predictors of mortality and suggests that these measures may be useful tools for identifying older individuals at higher risk of death. However, the findings also indicate a need for more research in younger populations and longer follow-up periods to confirm these associations.This systematic review and meta-analysis examines the associations between objective measures of physical capability (grip strength, walking speed, chair rising, and standing balance times) and mortality in community-dwelling populations. The review included published and unpublished data from observational studies, with a focus on all-cause mortality. The results consistently showed that individuals who performed poorly in these tests had a higher risk of mortality. For example, the summary hazard ratio for mortality comparing the weakest with the strongest quarter of grip strength was 1.67 (95% CI 1.45 to 1.93), and for walking speed, it was 2.87 (95% CI 2.22 to 3.72). The associations were found in both older and younger populations, although most studies were conducted in older adults (average age over 70 years). The review highlights the value of objective measures of physical capability as predictors of mortality and suggests that these measures may be useful tools for identifying older individuals at higher risk of death. However, the findings also indicate a need for more research in younger populations and longer follow-up periods to confirm these associations.
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[slides and audio] Objectively measured physical capability levels and mortality%3A systematic review and meta-analysis