The book "Optical-Thermal Response of Laser-Irradiated Tissue" presents the theory and applications of laser light interaction with tissue. It is divided into three parts: Tissue Optics, Thermal Interactions, and Medical Applications. The first part covers the fundamentals of light propagation in tissue, including diffusion approximation, adding-doubling, and Monte Carlo modeling. The second part discusses the thermal response of tissue to light, including heat conduction, temperature measurement, and tissue thermal properties. The third part focuses on medical applications of lasers, such as fiber optics, fluorescence, ablation, port wine stains, hyperthermia, and laser balloon angioplasty. Each chapter is written by a leading expert in the field, and the material is organized to progress from basic concepts to current understanding of laser-tissue interaction. The book emphasizes fundamental concepts rather than medical applications, providing a comprehensive overview of the optical and thermal responses of laser-irradiated tissue. It is intended to help analyze proposed medical applications of lasers and provide a basis for evaluating diagnostic systems and establishing dosimetry for therapeutic applications. The book includes detailed discussions on the physics of laser-tissue interactions, the measurement of tissue optical properties, and the thermal damage processes. It also covers various medical applications of lasers, including laser-induced hyperthermia, laser treatment of port wine stains, and laser balloon angioplasty. The book is a valuable resource for researchers and practitioners in the field of laser technology and biomedical engineering.The book "Optical-Thermal Response of Laser-Irradiated Tissue" presents the theory and applications of laser light interaction with tissue. It is divided into three parts: Tissue Optics, Thermal Interactions, and Medical Applications. The first part covers the fundamentals of light propagation in tissue, including diffusion approximation, adding-doubling, and Monte Carlo modeling. The second part discusses the thermal response of tissue to light, including heat conduction, temperature measurement, and tissue thermal properties. The third part focuses on medical applications of lasers, such as fiber optics, fluorescence, ablation, port wine stains, hyperthermia, and laser balloon angioplasty. Each chapter is written by a leading expert in the field, and the material is organized to progress from basic concepts to current understanding of laser-tissue interaction. The book emphasizes fundamental concepts rather than medical applications, providing a comprehensive overview of the optical and thermal responses of laser-irradiated tissue. It is intended to help analyze proposed medical applications of lasers and provide a basis for evaluating diagnostic systems and establishing dosimetry for therapeutic applications. The book includes detailed discussions on the physics of laser-tissue interactions, the measurement of tissue optical properties, and the thermal damage processes. It also covers various medical applications of lasers, including laser-induced hyperthermia, laser treatment of port wine stains, and laser balloon angioplasty. The book is a valuable resource for researchers and practitioners in the field of laser technology and biomedical engineering.