This book, "Optical-THERMAL Response of Laser-Irradiated Tissue," edited by Ashley J. Welch and Martin J. C. van Gemert, provides a comprehensive overview of the interaction between laser light and tissue. It is divided into three main parts: Tissue Optics, Thermal Interactions, and Medical Applications. The first part covers the fundamentals of light propagation in tissue, including steady-state and time-of-flight propagation, and the governing equations for light transport in scattering media. The second part delves into the thermal response of tissue to laser irradiation, discussing heat conduction, temperature measurement, and the effects of elevated temperatures on tissue components. The third part explores various medical applications of lasers, such as fiber optics, fluorescence spectroscopy, ablation, hyperthermia, and laser balloon angioplasty. Each chapter is authored by leading experts in the field, and the book aims to provide a solid foundation for understanding the fundamental interactions of laser light with tissue, which can be applied to the analysis and evaluation of medical laser systems.This book, "Optical-THERMAL Response of Laser-Irradiated Tissue," edited by Ashley J. Welch and Martin J. C. van Gemert, provides a comprehensive overview of the interaction between laser light and tissue. It is divided into three main parts: Tissue Optics, Thermal Interactions, and Medical Applications. The first part covers the fundamentals of light propagation in tissue, including steady-state and time-of-flight propagation, and the governing equations for light transport in scattering media. The second part delves into the thermal response of tissue to laser irradiation, discussing heat conduction, temperature measurement, and the effects of elevated temperatures on tissue components. The third part explores various medical applications of lasers, such as fiber optics, fluorescence spectroscopy, ablation, hyperthermia, and laser balloon angioplasty. Each chapter is authored by leading experts in the field, and the book aims to provide a solid foundation for understanding the fundamental interactions of laser light with tissue, which can be applied to the analysis and evaluation of medical laser systems.