2020-11-01 | Valentina O. Puntmann, MD, PhD; M. Ludovica Carej, MD; Imke Wieters, MD; Masia Fahim; Christophe Arendt, MD; Jedrzej Hoffmann, MD; Anastasia Shchendrygina, MD, PhD; Felicitas Escher, MD; Mariuca Vasa-Nicotera, MD; Andreas M. Zeiher, MD; Maria Vehreschild, MD; Eike Nagel, MD
This study evaluated the presence of myocardial injury in 100 unselected patients recently recovered from COVID-19. The patients, identified from the University Hospital Frankfurt COVID-19 Registry between April and June 2020, were compared with age- and sex-matched healthy controls and risk factor-matched patients. Cardiac magnetic resonance (CMR) imaging revealed that 78% of the patients had cardiac involvement, with 60% showing ongoing myocardial inflammation. These findings were independent of preexisting conditions, severity of the acute illness, and time from the original diagnosis. High-sensitivity troponin T levels were significantly elevated in 5% of the patients. Native T1 and T2 measures were the most discriminatory for detecting COVID-19-related myocardial pathology. The study highlights the need for ongoing investigation into the long-term cardiovascular consequences of COVID-19.This study evaluated the presence of myocardial injury in 100 unselected patients recently recovered from COVID-19. The patients, identified from the University Hospital Frankfurt COVID-19 Registry between April and June 2020, were compared with age- and sex-matched healthy controls and risk factor-matched patients. Cardiac magnetic resonance (CMR) imaging revealed that 78% of the patients had cardiac involvement, with 60% showing ongoing myocardial inflammation. These findings were independent of preexisting conditions, severity of the acute illness, and time from the original diagnosis. High-sensitivity troponin T levels were significantly elevated in 5% of the patients. Native T1 and T2 measures were the most discriminatory for detecting COVID-19-related myocardial pathology. The study highlights the need for ongoing investigation into the long-term cardiovascular consequences of COVID-19.