November 2020 | Valentina O. Puntmann, MD, PhD; M. Ludovica Carerj, MD; Imke Wieters, MD; Masia Fahim, MD; Christophe Arendt, MD; Jedrzej Hoffmann, MD; Anastasia Shchendrygina, MD, PhD; Felicitas Escher, MD; Mariuca Vasa-Nicotera, MD; Andreas M. Zeiher, MD; Maria Vehreschild, MD; Eike Nagel, MD
A study published in JAMA Cardiology evaluated the presence of myocardial injury in 100 patients recently recovered from coronavirus disease 2019 (COVID-19). The study used cardiovascular magnetic resonance (CMR) imaging to assess cardiac involvement in these patients. The results showed that 78% of patients had abnormal CMR findings, including elevated myocardial native T1 and T2 measures, myocardial late gadolinium enhancement, and pericardial enhancement. These findings indicated ongoing myocardial inflammation in 60% of patients, independent of preexisting conditions, severity of the illness, or time since diagnosis. High-sensitivity troponin T was significantly correlated with native T1 and T2 measures, suggesting myocardial inflammation. Endomyocardial biopsy in patients with severe findings revealed active lymphocytic inflammation. The study highlights the need for ongoing investigation of the long-term cardiovascular consequences of COVID-19. The findings suggest that even in patients with mild or no symptoms, there may be significant cardiac involvement, indicating the importance of further research to understand the long-term effects of the virus on the cardiovascular system.A study published in JAMA Cardiology evaluated the presence of myocardial injury in 100 patients recently recovered from coronavirus disease 2019 (COVID-19). The study used cardiovascular magnetic resonance (CMR) imaging to assess cardiac involvement in these patients. The results showed that 78% of patients had abnormal CMR findings, including elevated myocardial native T1 and T2 measures, myocardial late gadolinium enhancement, and pericardial enhancement. These findings indicated ongoing myocardial inflammation in 60% of patients, independent of preexisting conditions, severity of the illness, or time since diagnosis. High-sensitivity troponin T was significantly correlated with native T1 and T2 measures, suggesting myocardial inflammation. Endomyocardial biopsy in patients with severe findings revealed active lymphocytic inflammation. The study highlights the need for ongoing investigation of the long-term cardiovascular consequences of COVID-19. The findings suggest that even in patients with mild or no symptoms, there may be significant cardiac involvement, indicating the importance of further research to understand the long-term effects of the virus on the cardiovascular system.