**Molecular Genetics for the Clinician by D.J.H. Brock (Cambridge University Press, 1993, 289 pp.)**
This book is a user-friendly introduction to molecular genetics for clinicians, covering basic concepts from classical Mendelian genetics to gene therapy. It is concise, well-structured, and up-to-date, with recent references from 1992. The book highlights emerging areas like repeat sequences causing inherited diseases and discusses various techniques such as PCR, DNA sequencing, and Southern Hybridization. It also covers cytogenetic techniques, cancer genetics, and multifactorial disorders. The final chapter touches on the Human Genome Mapping Project and ethical issues in genetic disease investigation. The book is indexed and includes suggestions for further reading, making it a valuable resource for busy clinicians and medical students.
**Ovarian Cancer by S.C. Rubin & G.P. Sutton (Marcel Dekker, 1993, 498 pp.)**
This book provides a comprehensive overview of ovarian cancer, covering basic science, histopathology, and clinical management. It includes reviews on cancer genetics, oncogenes, and chemotherapy resistance. The histopathology section is extensive, and the clinical chapters cover various types of tumors. While there is some repetition and gaps in coverage, such as the lack of mention of peripheral blood stem cells in bone marrow transplantation, the book is well-organized and includes thought-provoking case histories. It addresses major surgical controversies and provides a balanced view of the disease's management. Overall, it is a valuable resource for both trainees and specialists in the field.
**Photodynamic Therapy: Basic Principles and Clinical Applications edited by B.W. Henderson & T.J. Dougherty (Marcel Dekker, 1992, 480 pp.)**
This multi-author book covers the development and applications of photodynamic therapy (PDT), also known as photochemotherapy. It includes recent advancements, such as the approval of Photofrin in Canada, and discusses potential second-generation sensitisers. The book explores the chemistry and physics of PDT, including the use of fiberoptic delivery systems and photodynamic dosimetry. It also delves into molecular biology aspects, such as stress responses and their transcriptional regulation. The clinical reports suggest that PDT has broad applications beyond cancer and holds promise for future therapeutic combinations.**Molecular Genetics for the Clinician by D.J.H. Brock (Cambridge University Press, 1993, 289 pp.)**
This book is a user-friendly introduction to molecular genetics for clinicians, covering basic concepts from classical Mendelian genetics to gene therapy. It is concise, well-structured, and up-to-date, with recent references from 1992. The book highlights emerging areas like repeat sequences causing inherited diseases and discusses various techniques such as PCR, DNA sequencing, and Southern Hybridization. It also covers cytogenetic techniques, cancer genetics, and multifactorial disorders. The final chapter touches on the Human Genome Mapping Project and ethical issues in genetic disease investigation. The book is indexed and includes suggestions for further reading, making it a valuable resource for busy clinicians and medical students.
**Ovarian Cancer by S.C. Rubin & G.P. Sutton (Marcel Dekker, 1993, 498 pp.)**
This book provides a comprehensive overview of ovarian cancer, covering basic science, histopathology, and clinical management. It includes reviews on cancer genetics, oncogenes, and chemotherapy resistance. The histopathology section is extensive, and the clinical chapters cover various types of tumors. While there is some repetition and gaps in coverage, such as the lack of mention of peripheral blood stem cells in bone marrow transplantation, the book is well-organized and includes thought-provoking case histories. It addresses major surgical controversies and provides a balanced view of the disease's management. Overall, it is a valuable resource for both trainees and specialists in the field.
**Photodynamic Therapy: Basic Principles and Clinical Applications edited by B.W. Henderson & T.J. Dougherty (Marcel Dekker, 1992, 480 pp.)**
This multi-author book covers the development and applications of photodynamic therapy (PDT), also known as photochemotherapy. It includes recent advancements, such as the approval of Photofrin in Canada, and discusses potential second-generation sensitisers. The book explores the chemistry and physics of PDT, including the use of fiberoptic delivery systems and photodynamic dosimetry. It also delves into molecular biology aspects, such as stress responses and their transcriptional regulation. The clinical reports suggest that PDT has broad applications beyond cancer and holds promise for future therapeutic combinations.