PATRIC is a comprehensive bacterial bioinformatics database and analysis resource. It provides researchers with an online platform that stores and integrates various data types, including genomics, transcriptomics, protein-protein interactions (PPIs), three-dimensional protein structures, and sequence typing data. All genomes in PATRIC are consistently annotated using RAST, an automated annotation system. PATRIC offers a variety of tools for researchers to find and analyze data, including a private workspace for storing genomic and gene associations. The database also includes integrated information related to disease and PPIs, and all data and analysis tools are freely available. PATRIC was established as a joint effort by two of the original National Institute of Allergy and Infectious Diseases-funded Bioinformatics Resource Centers (BRCs). It now hosts data from all NIAID priority pathogenic bacteria, including 22 genera, and includes data for all publicly available bacterial genomes. As of September 2013, over 10,000 bacterial genomes are available in PATRIC, with projections of over 15,000 by the end of the year. PATRIC integrates various 'omics datasets, including genomic, transcriptomic, proteomic, and structural data. The database also provides metadata for genomes, including isolation source, geographic location, and host/environment information. PATRIC includes transcriptomic data from thousands of gene expression datasets, and provides tools for researchers to analyze and compare these data. It also includes PPI data from public repositories, and provides tools for visualizing and analyzing these interactions. PATRIC also includes 3D protein structure data from public repositories, and provides tools for visualizing these structures. Additionally, PATRIC includes sequence typing data, allowing researchers to search for bacterial genomes based on sequence-based typing methods. PATRIC integrates data across sources, data types, molecular entities, and organisms. It provides tools for researchers to search, filter, and analyze data, including comparative genomic analysis tools. PATRIC also provides a private workspace for researchers to store and analyze their own data. The database supports multiple ways to access data, including APIs and FTP services for bulk downloads. PATRIC has expanded its analytical capabilities to include new data types, such as proteomics and metabolomics data. It also includes annotation enhancements for virulence factors and antibiotic resistance genes. PATRIC also supports the 'Bring Your Own Data' concept, allowing researchers to upload and analyze their own data. Future improvements include integrating additional data types and expanding the BYOD concept. PATRIC is funded by the National Institute of Allergy and Infectious Diseases and is a valuable resource for infectious disease researchers.PATRIC is a comprehensive bacterial bioinformatics database and analysis resource. It provides researchers with an online platform that stores and integrates various data types, including genomics, transcriptomics, protein-protein interactions (PPIs), three-dimensional protein structures, and sequence typing data. All genomes in PATRIC are consistently annotated using RAST, an automated annotation system. PATRIC offers a variety of tools for researchers to find and analyze data, including a private workspace for storing genomic and gene associations. The database also includes integrated information related to disease and PPIs, and all data and analysis tools are freely available. PATRIC was established as a joint effort by two of the original National Institute of Allergy and Infectious Diseases-funded Bioinformatics Resource Centers (BRCs). It now hosts data from all NIAID priority pathogenic bacteria, including 22 genera, and includes data for all publicly available bacterial genomes. As of September 2013, over 10,000 bacterial genomes are available in PATRIC, with projections of over 15,000 by the end of the year. PATRIC integrates various 'omics datasets, including genomic, transcriptomic, proteomic, and structural data. The database also provides metadata for genomes, including isolation source, geographic location, and host/environment information. PATRIC includes transcriptomic data from thousands of gene expression datasets, and provides tools for researchers to analyze and compare these data. It also includes PPI data from public repositories, and provides tools for visualizing and analyzing these interactions. PATRIC also includes 3D protein structure data from public repositories, and provides tools for visualizing these structures. Additionally, PATRIC includes sequence typing data, allowing researchers to search for bacterial genomes based on sequence-based typing methods. PATRIC integrates data across sources, data types, molecular entities, and organisms. It provides tools for researchers to search, filter, and analyze data, including comparative genomic analysis tools. PATRIC also provides a private workspace for researchers to store and analyze their own data. The database supports multiple ways to access data, including APIs and FTP services for bulk downloads. PATRIC has expanded its analytical capabilities to include new data types, such as proteomics and metabolomics data. It also includes annotation enhancements for virulence factors and antibiotic resistance genes. PATRIC also supports the 'Bring Your Own Data' concept, allowing researchers to upload and analyze their own data. Future improvements include integrating additional data types and expanding the BYOD concept. PATRIC is funded by the National Institute of Allergy and Infectious Diseases and is a valuable resource for infectious disease researchers.