The article reviews the role of Phytochrome-Interacting Factors (PIFs) in plant signaling pathways, particularly in regulating seed germination, seedling skotomorphogenesis, and shade avoidance. PIFs are a subset of basic helix-loop-helix transcription factors that interact with light-activated phytochromes to modulate gene expression. Light-activated phytochromes induce the rapid degradation of PIF proteins through phosphorylation and ubiquitination, reversing the repressive activities of PIFs. The review highlights recent advances in understanding the phy-PIF signaling pathway and emerging evidence that other pathways, such as the gibberellin pathway, circadian clock, and high temperature, also converge to regulate PIF activity. PIFs function as a cellular signaling hub, integrating multiple signals to orchestrate the transcriptional network that drives various morphogenic responses. The article also discusses the functional diversity among PIF family members and their roles in different developmental processes, including flowering, auxin signaling, and cell fate determination.The article reviews the role of Phytochrome-Interacting Factors (PIFs) in plant signaling pathways, particularly in regulating seed germination, seedling skotomorphogenesis, and shade avoidance. PIFs are a subset of basic helix-loop-helix transcription factors that interact with light-activated phytochromes to modulate gene expression. Light-activated phytochromes induce the rapid degradation of PIF proteins through phosphorylation and ubiquitination, reversing the repressive activities of PIFs. The review highlights recent advances in understanding the phy-PIF signaling pathway and emerging evidence that other pathways, such as the gibberellin pathway, circadian clock, and high temperature, also converge to regulate PIF activity. PIFs function as a cellular signaling hub, integrating multiple signals to orchestrate the transcriptional network that drives various morphogenic responses. The article also discusses the functional diversity among PIF family members and their roles in different developmental processes, including flowering, auxin signaling, and cell fate determination.