This paper explores the concept of path dependence and its relevance to regional economic evolution. Authors Ron Martin and Peter Sunley argue that path dependence and lock-in are place-dependent processes that require geographical explanation. They challenge the assumption that new technological-economic paths emerge randomly or spontaneously across space, instead suggesting that regional economies can either become locked into development paths that lose dynamism or reinvent themselves through new paths. The authors highlight unresolved issues surrounding the concept of path dependence, including its varying degrees and types, and its relationship with economic evolution. They also emphasize the importance of considering how geography influences the process of economic evolution. The paper concludes that while path dependence is an important feature of the economic landscape, the concept requires further elaboration to function as a core concept in an evolutionary economic geography. The authors also discuss the idea of regional path creation, arguing that the origins of technological, industrial, and regional paths are not purely random but are influenced by historical and contextual factors. They suggest that regional path dependence is a complex phenomenon that occurs at various spatial scales and involves the co-evolution of different arenas, including economic, technological, institutional, and socio-cultural. The paper calls for a more nuanced understanding of path dependence in economic geography, one that takes into account the role of place, history, and the interactions between different scales of economic activity.This paper explores the concept of path dependence and its relevance to regional economic evolution. Authors Ron Martin and Peter Sunley argue that path dependence and lock-in are place-dependent processes that require geographical explanation. They challenge the assumption that new technological-economic paths emerge randomly or spontaneously across space, instead suggesting that regional economies can either become locked into development paths that lose dynamism or reinvent themselves through new paths. The authors highlight unresolved issues surrounding the concept of path dependence, including its varying degrees and types, and its relationship with economic evolution. They also emphasize the importance of considering how geography influences the process of economic evolution. The paper concludes that while path dependence is an important feature of the economic landscape, the concept requires further elaboration to function as a core concept in an evolutionary economic geography. The authors also discuss the idea of regional path creation, arguing that the origins of technological, industrial, and regional paths are not purely random but are influenced by historical and contextual factors. They suggest that regional path dependence is a complex phenomenon that occurs at various spatial scales and involves the co-evolution of different arenas, including economic, technological, institutional, and socio-cultural. The paper calls for a more nuanced understanding of path dependence in economic geography, one that takes into account the role of place, history, and the interactions between different scales of economic activity.