The paper by Theresa Weldring and Sheree M.S. Smith discusses the increasing importance of patient-centered research and evaluation in healthcare to improve patient experience and ensure the robustness and value of medicinal products, therapies, and health services. It highlights the roles of patient-reported outcomes (PROs) and patient-reported outcome measures (PROMs) in this context. PROs are reports from patients about their health, quality of life, or functional status, while PROMs are tools used to measure these PROs. The paper also covers the Patient-Reported Experience Measures (PREMs) and the Patient and Public Involvement (PPI) initiative, which aim to involve patients in the research process. The authors emphasize the benefits and limitations of these approaches, including the need for valid, reliable, and responsive PROMs, and the importance of patient involvement in ensuring research relevance and quality. They also discuss the development and selection of PROMs, the challenges in comparing different PROMs, and the use of internet-based methods to improve feasibility and cost-effectiveness. The paper concludes by highlighting the growing international attention on PREMs as quality indicators and the value of PPI in healthcare research and service evaluation.The paper by Theresa Weldring and Sheree M.S. Smith discusses the increasing importance of patient-centered research and evaluation in healthcare to improve patient experience and ensure the robustness and value of medicinal products, therapies, and health services. It highlights the roles of patient-reported outcomes (PROs) and patient-reported outcome measures (PROMs) in this context. PROs are reports from patients about their health, quality of life, or functional status, while PROMs are tools used to measure these PROs. The paper also covers the Patient-Reported Experience Measures (PREMs) and the Patient and Public Involvement (PPI) initiative, which aim to involve patients in the research process. The authors emphasize the benefits and limitations of these approaches, including the need for valid, reliable, and responsive PROMs, and the importance of patient involvement in ensuring research relevance and quality. They also discuss the development and selection of PROMs, the challenges in comparing different PROMs, and the use of internet-based methods to improve feasibility and cost-effectiveness. The paper concludes by highlighting the growing international attention on PREMs as quality indicators and the value of PPI in healthcare research and service evaluation.