The Endocrine Society has published clinical practice guidelines for the assessment, treatment, and prevention of pediatric obesity. The guidelines emphasize the importance of early diagnosis and intervention to prevent long-term health complications. Key recommendations include using BMI and CDC normative percentiles to diagnose overweight and obesity in children and adolescents, evaluating potential comorbidities, and promoting healthy dietary and physical activity habits. Genetic testing is suggested for extreme early-onset obesity with specific clinical features or family history. Lifestyle modifications, including diet and physical activity, are recommended as first-line treatments, with pharmacotherapy and bariatric surgery reserved for severe cases. The guidelines also highlight the need for comprehensive behavioral interventions and family involvement in obesity prevention and treatment.The Endocrine Society has published clinical practice guidelines for the assessment, treatment, and prevention of pediatric obesity. The guidelines emphasize the importance of early diagnosis and intervention to prevent long-term health complications. Key recommendations include using BMI and CDC normative percentiles to diagnose overweight and obesity in children and adolescents, evaluating potential comorbidities, and promoting healthy dietary and physical activity habits. Genetic testing is suggested for extreme early-onset obesity with specific clinical features or family history. Lifestyle modifications, including diet and physical activity, are recommended as first-line treatments, with pharmacotherapy and bariatric surgery reserved for severe cases. The guidelines also highlight the need for comprehensive behavioral interventions and family involvement in obesity prevention and treatment.