This meta-analysis examines the relationship between perceived discrimination and both mental and physical health outcomes. The study analyzed 134 samples and found that perceived discrimination has a significant negative effect on mental and physical health. Perceived discrimination is also associated with heightened stress responses and unhealthy behaviors. The analysis tested several pathways through which perceived discrimination may affect health, including direct effects, stress responses, and health behaviors. The study also explored moderators such as social support, coping style, and group identity. The results suggest that perceived discrimination is linked to poorer mental and physical health, with no significant differences based on ethnicity or gender. The analysis provides a comprehensive understanding of the impact of perceived discrimination on health and highlights the need for interventions to address this issue.This meta-analysis examines the relationship between perceived discrimination and both mental and physical health outcomes. The study analyzed 134 samples and found that perceived discrimination has a significant negative effect on mental and physical health. Perceived discrimination is also associated with heightened stress responses and unhealthy behaviors. The analysis tested several pathways through which perceived discrimination may affect health, including direct effects, stress responses, and health behaviors. The study also explored moderators such as social support, coping style, and group identity. The results suggest that perceived discrimination is linked to poorer mental and physical health, with no significant differences based on ethnicity or gender. The analysis provides a comprehensive understanding of the impact of perceived discrimination on health and highlights the need for interventions to address this issue.