This article presents a sustainable method for producing high-performance polyamides using a carbohydrate-based core derived from agricultural waste. The study demonstrates a catalyst-free, melt polymerization process of dimethyl glyoxylate xylose (DMGX), a carbohydrate with 97% atom efficiency, into amorphous polyamides that match the performance of fossil-based semi-aromatic alternatives. These polyamides retain their thermomechanical properties through multiple rounds of high-shear mechanical recycling and can be chemically recycled. Techno-economic and life-cycle analyses suggest selling prices close to those of nylon 66, with a reduction of global warming potential (GWP) of up to 75%. The study highlights the versatility of a carbohydrate moiety in imparting performance comparable to semi-aromatic polymers across two important material chemistries. The research addresses the challenge of finding sustainable diacids compatible with both polyester and polyamide chemistries, similar to phthalic acids. The study shows that DMGX can be directly produced from abundant biomass at high yields and leads to degradable polyesters with well-rounded performance when polymerized with dialcohols. The synthesis of polyamides from DMGX was achieved through direct melt polycondensation with various aliphatic diamines, resulting in high-molecular-weight polyamides with excellent mechanical properties. The polyamides demonstrated high stiffness, strength, and ductility, with tensile moduli ranging from 1,700 to 2,250 MPa and elongation at break from 140 to 165%. The polyamides were also shown to be processable through various methods, including injection molding, extrusion, and 3D printing. Mechanical recycling of the polyamides was investigated, and the results showed that the tensile properties remained nearly identical across multiple recycling cycles. Chemical recycling of the polyamides was also explored, with high yields of DMGX and 1,8-diaminooctane achieved under mild conditions. The study also conducted a techno-economic analysis (TEA) and life-cycle assessment (LCA) of the polyamides, showing that the GWP of PA-8, DGX was significantly lower than that of nylon 66, with potential for further reduction if CO₂-derived glyoxylic acid is used. The results indicate that the polyamides offer a sustainable alternative to traditional plastics with high performance and environmental benefits.This article presents a sustainable method for producing high-performance polyamides using a carbohydrate-based core derived from agricultural waste. The study demonstrates a catalyst-free, melt polymerization process of dimethyl glyoxylate xylose (DMGX), a carbohydrate with 97% atom efficiency, into amorphous polyamides that match the performance of fossil-based semi-aromatic alternatives. These polyamides retain their thermomechanical properties through multiple rounds of high-shear mechanical recycling and can be chemically recycled. Techno-economic and life-cycle analyses suggest selling prices close to those of nylon 66, with a reduction of global warming potential (GWP) of up to 75%. The study highlights the versatility of a carbohydrate moiety in imparting performance comparable to semi-aromatic polymers across two important material chemistries. The research addresses the challenge of finding sustainable diacids compatible with both polyester and polyamide chemistries, similar to phthalic acids. The study shows that DMGX can be directly produced from abundant biomass at high yields and leads to degradable polyesters with well-rounded performance when polymerized with dialcohols. The synthesis of polyamides from DMGX was achieved through direct melt polycondensation with various aliphatic diamines, resulting in high-molecular-weight polyamides with excellent mechanical properties. The polyamides demonstrated high stiffness, strength, and ductility, with tensile moduli ranging from 1,700 to 2,250 MPa and elongation at break from 140 to 165%. The polyamides were also shown to be processable through various methods, including injection molding, extrusion, and 3D printing. Mechanical recycling of the polyamides was investigated, and the results showed that the tensile properties remained nearly identical across multiple recycling cycles. Chemical recycling of the polyamides was also explored, with high yields of DMGX and 1,8-diaminooctane achieved under mild conditions. The study also conducted a techno-economic analysis (TEA) and life-cycle assessment (LCA) of the polyamides, showing that the GWP of PA-8, DGX was significantly lower than that of nylon 66, with potential for further reduction if CO₂-derived glyoxylic acid is used. The results indicate that the polyamides offer a sustainable alternative to traditional plastics with high performance and environmental benefits.