Pericytes are cells surrounding small blood vessels, particularly capillaries, and play a key role in maintaining vascular integrity, angiogenesis, and blood flow. They also serve as a reservoir for multipotent stem/progenitor cells in various adipose tissues. Due to their heterogeneity, identifying and characterizing pericytes has been challenging. This review summarizes pericyte markers used in lineage-tracing studies, focusing on their role in adipogenesis and functions in different adipose tissues. Pericytes are involved in adipogenesis and have distinct markers depending on the tissue. Common markers include PDGFRβ, NG2, CD146, TBX18, α-SMA, and Nestin. These markers help identify pericytes in different adipose tissues, such as white, brown, beige, and bone marrow adipose tissues. However, these markers are also expressed in other cell types, making their use in identifying pericytes challenging. Pericytes in adipose tissue are involved in maintaining vascular integrity, facilitating angiogenesis, controlling blood flow, and serving as a stem/progenitor cell pool. They also contribute to the formation of the adipose tissue microenvironment. Pericytes have the capacity for self-renewal and differentiation into other cell lineages, such as mature adipocytes, osteoblasts, and other mesenchymal cells. They are also involved in bone marrow niches, where they support hematopoietic stem cell maintenance and regulate osteoblast, osteoclast, and adipocyte differentiation. Pericytes have been implicated in various physiological processes, including angiogenesis, tissue regeneration, and adipocyte differentiation. Their functions in adipose tissue include maintaining vascular integrity, facilitating angiogenesis, controlling blood flow, and serving as a stem/progenitor cell pool. Pericytes also contribute to the formation of the adipose tissue microenvironment and have the potential to influence metabolic health. The review highlights the importance of pericytes in adipose tissue and their potential as therapeutic targets for metabolic syndromes and bone-related diseases. Further research is needed to fully understand the mechanisms, triggers, and functional consequences of pericyte-to-adipocyte differentiation. Continued investigations will shed more light on the role of pericytes in adipose tissue biology and the progression of metabolic diseases related to adipose tissue.Pericytes are cells surrounding small blood vessels, particularly capillaries, and play a key role in maintaining vascular integrity, angiogenesis, and blood flow. They also serve as a reservoir for multipotent stem/progenitor cells in various adipose tissues. Due to their heterogeneity, identifying and characterizing pericytes has been challenging. This review summarizes pericyte markers used in lineage-tracing studies, focusing on their role in adipogenesis and functions in different adipose tissues. Pericytes are involved in adipogenesis and have distinct markers depending on the tissue. Common markers include PDGFRβ, NG2, CD146, TBX18, α-SMA, and Nestin. These markers help identify pericytes in different adipose tissues, such as white, brown, beige, and bone marrow adipose tissues. However, these markers are also expressed in other cell types, making their use in identifying pericytes challenging. Pericytes in adipose tissue are involved in maintaining vascular integrity, facilitating angiogenesis, controlling blood flow, and serving as a stem/progenitor cell pool. They also contribute to the formation of the adipose tissue microenvironment. Pericytes have the capacity for self-renewal and differentiation into other cell lineages, such as mature adipocytes, osteoblasts, and other mesenchymal cells. They are also involved in bone marrow niches, where they support hematopoietic stem cell maintenance and regulate osteoblast, osteoclast, and adipocyte differentiation. Pericytes have been implicated in various physiological processes, including angiogenesis, tissue regeneration, and adipocyte differentiation. Their functions in adipose tissue include maintaining vascular integrity, facilitating angiogenesis, controlling blood flow, and serving as a stem/progenitor cell pool. Pericytes also contribute to the formation of the adipose tissue microenvironment and have the potential to influence metabolic health. The review highlights the importance of pericytes in adipose tissue and their potential as therapeutic targets for metabolic syndromes and bone-related diseases. Further research is needed to fully understand the mechanisms, triggers, and functional consequences of pericyte-to-adipocyte differentiation. Continued investigations will shed more light on the role of pericytes in adipose tissue biology and the progression of metabolic diseases related to adipose tissue.