The article reviews the impact of agrochemicals, particularly pesticides, on food production, environmental health, and food safety. It highlights the historical increase in food production due to the use of fertilizers and pesticides, but also documents the widespread contamination of soils, terrestrial ecosystems, and aquatic systems with agrochemical residues. The toxic effects of these residues on human health and nonhuman biota are discussed, including their persistence in the environment and bioaccumulation in food chains. The article emphasizes the need for alternative approaches to intensive pesticide use, such as genetically modified organisms, organic farming, dietary changes, and advanced agricultural practices. It also calls for enhanced scientific research to develop safer and more sustainable methods of food production and environmental protection. The role of regulatory bodies and international agreements in controlling chemical residues and ensuring food security is addressed, along with the importance of public education and awareness in reducing exposure to toxic chemicals.The article reviews the impact of agrochemicals, particularly pesticides, on food production, environmental health, and food safety. It highlights the historical increase in food production due to the use of fertilizers and pesticides, but also documents the widespread contamination of soils, terrestrial ecosystems, and aquatic systems with agrochemical residues. The toxic effects of these residues on human health and nonhuman biota are discussed, including their persistence in the environment and bioaccumulation in food chains. The article emphasizes the need for alternative approaches to intensive pesticide use, such as genetically modified organisms, organic farming, dietary changes, and advanced agricultural practices. It also calls for enhanced scientific research to develop safer and more sustainable methods of food production and environmental protection. The role of regulatory bodies and international agreements in controlling chemical residues and ensuring food security is addressed, along with the importance of public education and awareness in reducing exposure to toxic chemicals.