The article "Physical Activity and Oxidative Stress in Aging" by Rosamaria Militello et al. explores the impact of physical activity on oxidative stress and aging. It highlights that regular physical activity can enhance antioxidant defenses, including enzymes like superoxide dismutase (SOD), catalase, and glutathione peroxidase, which help mitigate the negative effects of oxidative stress. However, intense or prolonged exercise can also increase reactive oxygen species (ROS) production, leading to exercise-induced oxidative stress. The relationship between physical activity and oxidative stress is complex and influenced by factors such as exercise type, intensity, duration, and frequency, as well as individual differences in antioxidant capacity and adaptation. The review discusses the role of physical activity in preventing and treating sarcopenia, an age-related disease characterized by muscle loss and weakness. It emphasizes that maintaining a balanced diet rich in antioxidants, regular exercise, and managing chronic conditions can help mitigate the negative effects of oxidative stress and improve overall health and longevity in older adults. The article also highlights the importance of finding the right balance in exercise routines to avoid excessive stress and injury. Additionally, the review examines the specific impacts of physical activity on aging in women, noting that menopause can lead to hormonal changes that affect bone density and estrogen levels. Regular physical activity can help alleviate these symptoms and improve overall well-being. The article concludes by emphasizing the need for healthcare and community support to encourage physical activity among the elderly, regardless of gender, to promote healthy aging and prevent age-related diseases.The article "Physical Activity and Oxidative Stress in Aging" by Rosamaria Militello et al. explores the impact of physical activity on oxidative stress and aging. It highlights that regular physical activity can enhance antioxidant defenses, including enzymes like superoxide dismutase (SOD), catalase, and glutathione peroxidase, which help mitigate the negative effects of oxidative stress. However, intense or prolonged exercise can also increase reactive oxygen species (ROS) production, leading to exercise-induced oxidative stress. The relationship between physical activity and oxidative stress is complex and influenced by factors such as exercise type, intensity, duration, and frequency, as well as individual differences in antioxidant capacity and adaptation. The review discusses the role of physical activity in preventing and treating sarcopenia, an age-related disease characterized by muscle loss and weakness. It emphasizes that maintaining a balanced diet rich in antioxidants, regular exercise, and managing chronic conditions can help mitigate the negative effects of oxidative stress and improve overall health and longevity in older adults. The article also highlights the importance of finding the right balance in exercise routines to avoid excessive stress and injury. Additionally, the review examines the specific impacts of physical activity on aging in women, noting that menopause can lead to hormonal changes that affect bone density and estrogen levels. Regular physical activity can help alleviate these symptoms and improve overall well-being. The article concludes by emphasizing the need for healthcare and community support to encourage physical activity among the elderly, regardless of gender, to promote healthy aging and prevent age-related diseases.