This review discusses the role of plant hormones in mediating stress responses, focusing on the intricate signaling networks and crosstalk between different hormone pathways. Abiotic stresses such as drought, heat, cold, and salinity, and biotic stresses from pathogens, insects, and nematodes, are common challenges for plants. Phytohormones, including abscisic acid (ABA), salicylic acid (SA), jasmonates (JA), and ethylene (ET), play critical roles in helping plants adapt to these adverse conditions. The review highlights how these hormones regulate stress responses through complex signaling networks and crosstalk between their signaling pathways. For instance, ABA is crucial for drought and salt stress responses, while SA, JA, and ET are involved in defense against pathogens and pests. The crosstalk between these hormones, such as the antagonistic and synergistic interactions, is essential for the plant's overall stress response. The review also discusses the role of growth-promoting hormones like gibberellins (GA), auxins, and cytokinins in mediating stress responses and their interactions with other hormones. The discussion on seed dormancy and germination illustrates the fine balance maintained by ABA and GA in regulating plant responses to environmental signals. Overall, the review emphasizes the importance of understanding the complex crosstalk among plant hormones for improving stress tolerance in crops.This review discusses the role of plant hormones in mediating stress responses, focusing on the intricate signaling networks and crosstalk between different hormone pathways. Abiotic stresses such as drought, heat, cold, and salinity, and biotic stresses from pathogens, insects, and nematodes, are common challenges for plants. Phytohormones, including abscisic acid (ABA), salicylic acid (SA), jasmonates (JA), and ethylene (ET), play critical roles in helping plants adapt to these adverse conditions. The review highlights how these hormones regulate stress responses through complex signaling networks and crosstalk between their signaling pathways. For instance, ABA is crucial for drought and salt stress responses, while SA, JA, and ET are involved in defense against pathogens and pests. The crosstalk between these hormones, such as the antagonistic and synergistic interactions, is essential for the plant's overall stress response. The review also discusses the role of growth-promoting hormones like gibberellins (GA), auxins, and cytokinins in mediating stress responses and their interactions with other hormones. The discussion on seed dormancy and germination illustrates the fine balance maintained by ABA and GA in regulating plant responses to environmental signals. Overall, the review emphasizes the importance of understanding the complex crosstalk among plant hormones for improving stress tolerance in crops.