This review discusses the role of plant hormones in mediating stress responses to abiotic and biotic stresses. It highlights the importance of hormone signaling networks and their crosstalk in enabling plants to adapt to adverse environmental conditions. The major plant hormones involved in stress responses include abscisic acid (ABA), salicylic acid (SA), jasmonates (JA), and ethylene (ET). ABA is primarily involved in abiotic stress responses, such as drought, salinity, and cold, while SA, JA, and ET are mainly involved in biotic stress responses, such as pathogen and herbivore defense. The review also discusses the crosstalk between these hormones and other growth-promoting hormones, such as gibberellins (GA), auxins, and cytokinins. The crosstalk between different hormones is essential for generating a sophisticated and efficient stress response. The review also discusses the role of ABA and GA in regulating seed dormancy and germination, which is crucial for evading early abiotic stress conditions. The intricate crosstalk among plant hormones is a key factor in plant stress response and development. Understanding these crosstalk mechanisms is important for improving stress tolerance in crops. The review emphasizes the need for further research into the molecular mechanisms of hormone crosstalk to better understand plant development and improve crop resilience to environmental stresses.This review discusses the role of plant hormones in mediating stress responses to abiotic and biotic stresses. It highlights the importance of hormone signaling networks and their crosstalk in enabling plants to adapt to adverse environmental conditions. The major plant hormones involved in stress responses include abscisic acid (ABA), salicylic acid (SA), jasmonates (JA), and ethylene (ET). ABA is primarily involved in abiotic stress responses, such as drought, salinity, and cold, while SA, JA, and ET are mainly involved in biotic stress responses, such as pathogen and herbivore defense. The review also discusses the crosstalk between these hormones and other growth-promoting hormones, such as gibberellins (GA), auxins, and cytokinins. The crosstalk between different hormones is essential for generating a sophisticated and efficient stress response. The review also discusses the role of ABA and GA in regulating seed dormancy and germination, which is crucial for evading early abiotic stress conditions. The intricate crosstalk among plant hormones is a key factor in plant stress response and development. Understanding these crosstalk mechanisms is important for improving stress tolerance in crops. The review emphasizes the need for further research into the molecular mechanisms of hormone crosstalk to better understand plant development and improve crop resilience to environmental stresses.