The article introduces a wireless theranostic patch designed to address the challenges of chronic, non-healing wounds, particularly in diabetic patients. The patch integrates advanced materials that are both multifunctional and electro-responsive, leveraging a blend of smart hydrogels and wearable bioelectronics to support optimal wound healing. The core of the patch is a conductive polymer hydrogel (MFCPH) that delivers a stretchable, antimicrobial, and moist environment for the wound, with added benefits such as conductivity and visibility. The materials also enable continuous and autonomous monitoring of glucose and pH levels, allowing for precise and personalized treatments like insulin delivery via iontophoresis and electrical stimulation. Animal models have demonstrated that this integrated system is highly adaptable, effectively promoting wound closure and healing. The wireless theranostic system offers an exciting prospect for personalized healthcare solutions, adopting a patient-centric approach that prioritizes real-time, targeted care for chronic wounds. Its incorporation of advanced materials and electro-controlled treatments paves the way for new and innovative approaches to wound management.The article introduces a wireless theranostic patch designed to address the challenges of chronic, non-healing wounds, particularly in diabetic patients. The patch integrates advanced materials that are both multifunctional and electro-responsive, leveraging a blend of smart hydrogels and wearable bioelectronics to support optimal wound healing. The core of the patch is a conductive polymer hydrogel (MFCPH) that delivers a stretchable, antimicrobial, and moist environment for the wound, with added benefits such as conductivity and visibility. The materials also enable continuous and autonomous monitoring of glucose and pH levels, allowing for precise and personalized treatments like insulin delivery via iontophoresis and electrical stimulation. Animal models have demonstrated that this integrated system is highly adaptable, effectively promoting wound closure and healing. The wireless theranostic system offers an exciting prospect for personalized healthcare solutions, adopting a patient-centric approach that prioritizes real-time, targeted care for chronic wounds. Its incorporation of advanced materials and electro-controlled treatments paves the way for new and innovative approaches to wound management.