Potential Role of Carotenoids as Antioxidants in Human Health and Disease

Potential Role of Carotenoids as Antioxidants in Human Health and Disease

27 January 2014 | Joanna Fiedor * and Květoslava Burda
Carotenoids are a diverse group of isoprenoid pigments with strong antioxidant properties, playing a crucial role in protecting against oxidative stress and related diseases. They efficiently quench singlet oxygen and scavenge reactive oxygen species (ROS), contributing to the prevention of chronic diseases such as cancer, cardiovascular disease, and photosensitivity disorders. Carotenoids are found in various foods and tissues, and their bioavailability is influenced by factors like diet, absorption, and interactions with other compounds. Despite their potential benefits, the exact mechanisms of their function in the body remain unclear. Studies suggest that adequate carotenoid intake, either through diet or supplements, may reduce the risk of several ROS-mediated disorders. However, some studies have shown conflicting results, indicating that the relationship between carotenoids and disease is complex. Carotenoids, particularly beta-carotene, lutein, and zeaxanthin, are important for eye health and may help prevent age-related macular degeneration and cataracts. They also support immune function and may have protective effects against photosensitivity disorders. Overall, while carotenoids show promise as antioxidants, more research is needed to fully understand their role in human health.Carotenoids are a diverse group of isoprenoid pigments with strong antioxidant properties, playing a crucial role in protecting against oxidative stress and related diseases. They efficiently quench singlet oxygen and scavenge reactive oxygen species (ROS), contributing to the prevention of chronic diseases such as cancer, cardiovascular disease, and photosensitivity disorders. Carotenoids are found in various foods and tissues, and their bioavailability is influenced by factors like diet, absorption, and interactions with other compounds. Despite their potential benefits, the exact mechanisms of their function in the body remain unclear. Studies suggest that adequate carotenoid intake, either through diet or supplements, may reduce the risk of several ROS-mediated disorders. However, some studies have shown conflicting results, indicating that the relationship between carotenoids and disease is complex. Carotenoids, particularly beta-carotene, lutein, and zeaxanthin, are important for eye health and may help prevent age-related macular degeneration and cataracts. They also support immune function and may have protective effects against photosensitivity disorders. Overall, while carotenoids show promise as antioxidants, more research is needed to fully understand their role in human health.
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