The article discusses the potential sexual transmission of Zika virus (ZIKV) based on a case study from Tahiti, French Polynesia, during the 2013 ZIKV outbreak. A 44-year-old man experienced symptoms of ZIKV infection and later sought treatment for hematospermia. ZIKV was isolated from his semen, supporting the hypothesis that ZIKV can be transmitted sexually. The study detected high levels of ZIKV RNA in the semen and urine samples, but not in the blood, suggesting that viral replication may have occurred in the genital tract. This finding is consistent with previous reports of other flaviviruses being detected in urine and semen. The authors conclude that their findings support the hypothesis that ZIKV can be transmitted by sexual intercourse and suggest that urine samples may be useful for late diagnosis of ZIKV infections.The article discusses the potential sexual transmission of Zika virus (ZIKV) based on a case study from Tahiti, French Polynesia, during the 2013 ZIKV outbreak. A 44-year-old man experienced symptoms of ZIKV infection and later sought treatment for hematospermia. ZIKV was isolated from his semen, supporting the hypothesis that ZIKV can be transmitted sexually. The study detected high levels of ZIKV RNA in the semen and urine samples, but not in the blood, suggesting that viral replication may have occurred in the genital tract. This finding is consistent with previous reports of other flaviviruses being detected in urine and semen. The authors conclude that their findings support the hypothesis that ZIKV can be transmitted by sexual intercourse and suggest that urine samples may be useful for late diagnosis of ZIKV infections.