This paper proposes different configurations for maximum power extraction from photovoltaic (PV) arrays under partial shading conditions. The study investigates the impact of partial shading on PV arrays and evaluates various array configurations to minimize mismatch losses and power loss. The proposed configurations aim to enhance power output by optimizing the arrangement of PV modules. Simulations and experimental setups were conducted using MATLAB Simulink for a 4×4 PV array under different shading patterns. The results show that certain configurations significantly improve power output and reduce mismatch losses. For example, configuration-10 provides the highest power output with minimal mismatch and power loss under various shading conditions. The study also compares different configurations under various partial shading scenarios, highlighting the effectiveness of specific configurations in enhancing power generation. The findings suggest that selecting the optimal configuration based on shading patterns is crucial for maximizing power output from PV arrays. The research contributes to the development of more efficient PV systems by providing insights into array configurations that mitigate the effects of partial shading.This paper proposes different configurations for maximum power extraction from photovoltaic (PV) arrays under partial shading conditions. The study investigates the impact of partial shading on PV arrays and evaluates various array configurations to minimize mismatch losses and power loss. The proposed configurations aim to enhance power output by optimizing the arrangement of PV modules. Simulations and experimental setups were conducted using MATLAB Simulink for a 4×4 PV array under different shading patterns. The results show that certain configurations significantly improve power output and reduce mismatch losses. For example, configuration-10 provides the highest power output with minimal mismatch and power loss under various shading conditions. The study also compares different configurations under various partial shading scenarios, highlighting the effectiveness of specific configurations in enhancing power generation. The findings suggest that selecting the optimal configuration based on shading patterns is crucial for maximizing power output from PV arrays. The research contributes to the development of more efficient PV systems by providing insights into array configurations that mitigate the effects of partial shading.