The American Society of Anesthesiologists (ASA) has developed guidelines for sedation and analgesia by non-anesthesiologists. These guidelines aim to help practitioners provide safe and effective sedation/analgesia while minimizing risks. The guidelines define levels of sedation, including moderate sedation (conscious sedation) and deep sedation, and emphasize the importance of proper patient evaluation, monitoring, and training. They also address the need for appropriate equipment, emergency preparedness, and recovery care. The guidelines are based on current evidence and expert opinion, and they are subject to revision as new information becomes available. The guidelines recommend that practitioners be able to manage and rescue patients who may become more sedated than intended. They also emphasize the importance of preprocedure counseling, fasting, and monitoring of vital signs and respiratory function. The guidelines are intended for use in a variety of settings and by practitioners who are not specialists in anesthesiology. The guidelines are not intended for minimal sedation (anxiolysis) or general anesthesia. The guidelines also emphasize the importance of having trained personnel available for patient monitoring and the availability of emergency equipment and reversal agents. The guidelines are based on a systematic review of the literature and expert opinion, and they are intended to be used as a reference for clinical practice.The American Society of Anesthesiologists (ASA) has developed guidelines for sedation and analgesia by non-anesthesiologists. These guidelines aim to help practitioners provide safe and effective sedation/analgesia while minimizing risks. The guidelines define levels of sedation, including moderate sedation (conscious sedation) and deep sedation, and emphasize the importance of proper patient evaluation, monitoring, and training. They also address the need for appropriate equipment, emergency preparedness, and recovery care. The guidelines are based on current evidence and expert opinion, and they are subject to revision as new information becomes available. The guidelines recommend that practitioners be able to manage and rescue patients who may become more sedated than intended. They also emphasize the importance of preprocedure counseling, fasting, and monitoring of vital signs and respiratory function. The guidelines are intended for use in a variety of settings and by practitioners who are not specialists in anesthesiology. The guidelines are not intended for minimal sedation (anxiolysis) or general anesthesia. The guidelines also emphasize the importance of having trained personnel available for patient monitoring and the availability of emergency equipment and reversal agents. The guidelines are based on a systematic review of the literature and expert opinion, and they are intended to be used as a reference for clinical practice.