Researchers predict that LaSc₂H₂₄, a new hydrogen clathrate hydride, could exhibit superconductivity at temperatures above room temperature under high pressure. The study, using computational methods, identifies a thermodynamically stable structure composed of H₂₄ and H₃₀ hydrogen cages at pressures up to 300 GPa. LaSc₂H₂₄ is calculated to have a superconducting critical temperature (Tc) of up to 331 K at 250 GPa and 316 K at 167 GPa, with anharmonic effects considered. The high Tc is attributed to a large hydrogen-derived density of states at the Fermi level, arising from the unique H₂₄ and H₃₀ cages. The introduction of Sc in the La–H system is expected to enhance superconductivity by modifying the electronic structure and increasing the Debye temperature. The study also shows that LaSc₂H₂₄ is dynamically stable down to 150 GPa, with a predicted Tc of 331 K at 250 GPa. The results suggest that ternary hydrides offer a promising platform for engineering high-temperature superconductors, with LaSc₂H₂₄ being one of the highest Tc superconductors predicted so far. The findings highlight the potential of incorporating additional elements into hydrides to achieve higher Tc values and expand the range of superconducting materials. The study also emphasizes the importance of considering anharmonic effects in predicting superconducting properties under high pressure.Researchers predict that LaSc₂H₂₄, a new hydrogen clathrate hydride, could exhibit superconductivity at temperatures above room temperature under high pressure. The study, using computational methods, identifies a thermodynamically stable structure composed of H₂₄ and H₃₀ hydrogen cages at pressures up to 300 GPa. LaSc₂H₂₄ is calculated to have a superconducting critical temperature (Tc) of up to 331 K at 250 GPa and 316 K at 167 GPa, with anharmonic effects considered. The high Tc is attributed to a large hydrogen-derived density of states at the Fermi level, arising from the unique H₂₄ and H₃₀ cages. The introduction of Sc in the La–H system is expected to enhance superconductivity by modifying the electronic structure and increasing the Debye temperature. The study also shows that LaSc₂H₂₄ is dynamically stable down to 150 GPa, with a predicted Tc of 331 K at 250 GPa. The results suggest that ternary hydrides offer a promising platform for engineering high-temperature superconductors, with LaSc₂H₂₄ being one of the highest Tc superconductors predicted so far. The findings highlight the potential of incorporating additional elements into hydrides to achieve higher Tc values and expand the range of superconducting materials. The study also emphasizes the importance of considering anharmonic effects in predicting superconducting properties under high pressure.