This study reports the projected cancer incidence and mortality in Korea for 2024. Based on data from 1999 to 2021, the researchers used linear regression models to estimate the number of new cancer cases and deaths. The results indicate that 292,221 new cancer cases and 83,770 cancer deaths are expected in 2024. The most common cancer sites are thyroid, colon and rectum, lung, breast, and stomach, accounting for 55.7% of the overall cancer burden. Lung cancer is expected to be the leading cause of cancer death, followed by liver, colorectal, pancreatic, and stomach cancers. The age-standardized incidence rates for female breast and prostate cancers are estimated to continue to increase. The study highlights the importance of these projections for planning and evaluating cancer-control programs in Korea. The researchers caution that the estimates are model-based and may be affected by factors such as the coronavirus disease 2019 epidemic and changes in diagnostic criteria. The study also acknowledges the contributions of various institutions and individuals in data collection and analysis. The findings emphasize the growing burden of cancer in Korea, particularly among the aging population. The projections provide an important resource for public health planning and policy-making.This study reports the projected cancer incidence and mortality in Korea for 2024. Based on data from 1999 to 2021, the researchers used linear regression models to estimate the number of new cancer cases and deaths. The results indicate that 292,221 new cancer cases and 83,770 cancer deaths are expected in 2024. The most common cancer sites are thyroid, colon and rectum, lung, breast, and stomach, accounting for 55.7% of the overall cancer burden. Lung cancer is expected to be the leading cause of cancer death, followed by liver, colorectal, pancreatic, and stomach cancers. The age-standardized incidence rates for female breast and prostate cancers are estimated to continue to increase. The study highlights the importance of these projections for planning and evaluating cancer-control programs in Korea. The researchers caution that the estimates are model-based and may be affected by factors such as the coronavirus disease 2019 epidemic and changes in diagnostic criteria. The study also acknowledges the contributions of various institutions and individuals in data collection and analysis. The findings emphasize the growing burden of cancer in Korea, particularly among the aging population. The projections provide an important resource for public health planning and policy-making.