Profex is a graphical user interface (GUI) for the Rietveld refinement program BGMN. It provides direct access to BGMN input files, preserving its powerful and flexible scripting features. Profex enables efficient workflows for single or batch refinements by managing control and structure files, providing dialogues and shortcuts for operations, performing operations in the background, and offering import filters for CIF and XML crystal structure files. Refinement results can be easily exported for further processing. State-of-the-art graphical export of diffraction patterns to pixel and vector graphics formats allows the creation of publication-quality graphs with minimal effort. Profex reads and converts a variety of proprietary raw data formats, making it largely instrument independent. Profex and BGMN are available under an open-source license for Windows, Linux, and OS X. Profex was developed to provide an efficient GUI for text-file-based academic Rietveld refinement programs, allowing users to edit text files without shielding them from the process. It supports a wide range of raw data file formats and provides tools for importing, processing, and exporting data. The program is written in C++ using the Qt toolkit and supports major operating systems. It includes features such as a plot display area for raw data scans and refined patterns, text editors for input files, and a variety of GUI elements for managing projects and results. Profex supports batch processing, allowing the simultaneous processing of multiple data sets. It simplifies the creation and management of refinement projects by automating tasks such as converting raw data files, copying structure and device files, and managing GOALs. The program also provides features for exporting results, including global and local GOALs, and allows for the customization of chemical compositions based on refined phase quantities. Profex includes a context help feature that assists users in understanding parameters and options in structure and control files. It also supports the creation of structure and device files, allowing users to generate STR files from CIF or ICDD XML formats. The program is platform-independent and freely available under an open-source license. Profex is designed to be user-friendly, with a low level of abstraction that preserves BGMN's scripting capabilities while providing a comprehensive tool for Rietveld refinement of powder XRD data.Profex is a graphical user interface (GUI) for the Rietveld refinement program BGMN. It provides direct access to BGMN input files, preserving its powerful and flexible scripting features. Profex enables efficient workflows for single or batch refinements by managing control and structure files, providing dialogues and shortcuts for operations, performing operations in the background, and offering import filters for CIF and XML crystal structure files. Refinement results can be easily exported for further processing. State-of-the-art graphical export of diffraction patterns to pixel and vector graphics formats allows the creation of publication-quality graphs with minimal effort. Profex reads and converts a variety of proprietary raw data formats, making it largely instrument independent. Profex and BGMN are available under an open-source license for Windows, Linux, and OS X. Profex was developed to provide an efficient GUI for text-file-based academic Rietveld refinement programs, allowing users to edit text files without shielding them from the process. It supports a wide range of raw data file formats and provides tools for importing, processing, and exporting data. The program is written in C++ using the Qt toolkit and supports major operating systems. It includes features such as a plot display area for raw data scans and refined patterns, text editors for input files, and a variety of GUI elements for managing projects and results. Profex supports batch processing, allowing the simultaneous processing of multiple data sets. It simplifies the creation and management of refinement projects by automating tasks such as converting raw data files, copying structure and device files, and managing GOALs. The program also provides features for exporting results, including global and local GOALs, and allows for the customization of chemical compositions based on refined phase quantities. Profex includes a context help feature that assists users in understanding parameters and options in structure and control files. It also supports the creation of structure and device files, allowing users to generate STR files from CIF or ICDD XML formats. The program is platform-independent and freely available under an open-source license. Profex is designed to be user-friendly, with a low level of abstraction that preserves BGMN's scripting capabilities while providing a comprehensive tool for Rietveld refinement of powder XRD data.