The Chemical Analysis Working Group (CAWG) of the Metabolomics Standards Initiative (MSI) proposes minimum reporting standards for chemical analysis in metabolomics experiments. These standards aim to ensure consistency, reproducibility, and utility of metabolomics data by providing a framework for reporting metadata related to sample preparation, experimental analysis, quality control, metabolite identification, and data preprocessing. The standards focus on mass spectrometry and nuclear magnetic resonance (NMR) due to their prevalence in metabolomics, but are intended to apply to all analytical techniques. The CAWG encourages input from the scientific community to refine these standards and develop a comprehensive set of reporting guidelines. The proposed standards include detailed metadata for sample preparation, chromatography, mass spectrometry, NMR, stable isotopes, FT-IR spectroscopy, instrumental performance, method validation, and data preprocessing. These standards emphasize the importance of accurate and reproducible data, ensuring that metabolomics experiments are well-documented and can be replicated by other researchers. The CAWG also recommends that metabolite identifications be rigorous, with multiple data points to confirm the identity of compounds. For unknown metabolites, unique spectral or chromatographic features should be reported to facilitate their identification. The standards aim to enhance the quality and utility of metabolomics data by promoting standardized reporting practices. The CAWG invites feedback from the scientific community to further refine these standards and improve the overall quality of metabolomics research.The Chemical Analysis Working Group (CAWG) of the Metabolomics Standards Initiative (MSI) proposes minimum reporting standards for chemical analysis in metabolomics experiments. These standards aim to ensure consistency, reproducibility, and utility of metabolomics data by providing a framework for reporting metadata related to sample preparation, experimental analysis, quality control, metabolite identification, and data preprocessing. The standards focus on mass spectrometry and nuclear magnetic resonance (NMR) due to their prevalence in metabolomics, but are intended to apply to all analytical techniques. The CAWG encourages input from the scientific community to refine these standards and develop a comprehensive set of reporting guidelines. The proposed standards include detailed metadata for sample preparation, chromatography, mass spectrometry, NMR, stable isotopes, FT-IR spectroscopy, instrumental performance, method validation, and data preprocessing. These standards emphasize the importance of accurate and reproducible data, ensuring that metabolomics experiments are well-documented and can be replicated by other researchers. The CAWG also recommends that metabolite identifications be rigorous, with multiple data points to confirm the identity of compounds. For unknown metabolites, unique spectral or chromatographic features should be reported to facilitate their identification. The standards aim to enhance the quality and utility of metabolomics data by promoting standardized reporting practices. The CAWG invites feedback from the scientific community to further refine these standards and improve the overall quality of metabolomics research.