Proposed minimum reporting standards for chemical analysis Chemical Analysis Working Group (CAWG) Metabolomics Standards Initiative (MSI)

Proposed minimum reporting standards for chemical analysis Chemical Analysis Working Group (CAWG) Metabolomics Standards Initiative (MSI)

2007 September ; 3(3): 211–221 | Lloyd W. Sumner, Alexander Amberg, Dave Barrett, Michael H. Beale, Richard Beger, Clare A. Daykin, Teresa W.-M. Fan, Oliver Fiehn, Royston Goodacre, Julian L. Griffin, Thomas Hankemeier, Nigel Hardy, James Harnly, Richard Higashi, Joachim Kopka, Andrew N. Lane, John C. Lindon, Philip Marriott, Andrew W. Nicholls, Michael D. Reily, John J. Thaden, Mark R. Viant
The Chemical Analysis Working Group (CAWG) of the Metabolomics Standards Initiative (MSI) has proposed minimum reporting standards for chemical analysis in metabolomics experiments. These standards aim to provide a biological and empirical context for the data, facilitate experimental replication, and enable re-interrogation and comparison of data by others. The proposed standards focus on sample preparation, experimental analysis, quality control, metabolite identification, and data preprocessing, with a particular emphasis on mass spectrometry and nuclear magnetic resonance spectroscopy. The CAWG welcomes input from the community through an online discussion forum and aims to develop consistent and appropriate descriptors to support the dissemination and reuse of metabolomic data. The standards are designed to maximize the utility of the data for other researchers, without prescribing specific practices but rather describing the experimental methods. The CAWG will continue to work on a consensus document and integrate it with other MSI groups to establish acceptable practices that enhance the validity and understanding of metabolomics data.The Chemical Analysis Working Group (CAWG) of the Metabolomics Standards Initiative (MSI) has proposed minimum reporting standards for chemical analysis in metabolomics experiments. These standards aim to provide a biological and empirical context for the data, facilitate experimental replication, and enable re-interrogation and comparison of data by others. The proposed standards focus on sample preparation, experimental analysis, quality control, metabolite identification, and data preprocessing, with a particular emphasis on mass spectrometry and nuclear magnetic resonance spectroscopy. The CAWG welcomes input from the community through an online discussion forum and aims to develop consistent and appropriate descriptors to support the dissemination and reuse of metabolomic data. The standards are designed to maximize the utility of the data for other researchers, without prescribing specific practices but rather describing the experimental methods. The CAWG will continue to work on a consensus document and integrate it with other MSI groups to establish acceptable practices that enhance the validity and understanding of metabolomics data.
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