The article discusses the relationship between psychosocial factors at work and musculoskeletal disorders (MSD). Traditionally, research on occupational stress and MSDs have been separate, with stress researchers focusing on role stressors and MSD researchers on physical workload factors. However, recent studies show that psychosocial factors, such as job demands, job variety, autonomy, and social support, are also important in MSD development. Poorly designed work environments can lead to psychological harm and physical issues like back problems. Physical factors can also affect stress and health through cognitive processes, such as anticipation or worrying, which can disrupt sleep and negatively impact health. The article emphasizes that both physical and psychosocial factors contribute to MSDs, and that the stress response can be caused by either or both. It also highlights the importance of interdisciplinary research to bridge the gap between stress research and MSD epidemiology. The article references studies that test hypotheses about the causal pathways between work stressors and MSDs, such as the "Cinderella model" and the "Brussels model." These models suggest that physical and psychosocial factors interact to cause MSDs. The article concludes that integrating research on psychosocial factors with MSD research is essential for understanding and preventing MSDs. It also highlights the importance of using multi-method approaches, biological markers, and longitudinal studies to better understand the relationship between work stressors and MSDs. The article encourages interdisciplinary research to improve understanding and prevention of MSDs.The article discusses the relationship between psychosocial factors at work and musculoskeletal disorders (MSD). Traditionally, research on occupational stress and MSDs have been separate, with stress researchers focusing on role stressors and MSD researchers on physical workload factors. However, recent studies show that psychosocial factors, such as job demands, job variety, autonomy, and social support, are also important in MSD development. Poorly designed work environments can lead to psychological harm and physical issues like back problems. Physical factors can also affect stress and health through cognitive processes, such as anticipation or worrying, which can disrupt sleep and negatively impact health. The article emphasizes that both physical and psychosocial factors contribute to MSDs, and that the stress response can be caused by either or both. It also highlights the importance of interdisciplinary research to bridge the gap between stress research and MSD epidemiology. The article references studies that test hypotheses about the causal pathways between work stressors and MSDs, such as the "Cinderella model" and the "Brussels model." These models suggest that physical and psychosocial factors interact to cause MSDs. The article concludes that integrating research on psychosocial factors with MSD research is essential for understanding and preventing MSDs. It also highlights the importance of using multi-method approaches, biological markers, and longitudinal studies to better understand the relationship between work stressors and MSDs. The article encourages interdisciplinary research to improve understanding and prevention of MSDs.