This systematic review by Puhan et al. (2009) evaluates the effects of pulmonary rehabilitation on patients with Chronic Obstructive Pulmonary Disease (COPD) following an exacerbation. The review aimed to assess the impact on future hospital admissions, mortality, health-related quality of life, and exercise capacity. Six randomized controlled trials involving 219 patients were included. The results showed that pulmonary rehabilitation significantly reduced hospital admissions (pooled odds ratio 0.13, NNT 3) and mortality (pooled odds ratio 0.29, NNT 6) over the study periods. It also improved health-related quality of life and exercise capacity, with improvements in various domains of the Chronic Respiratory Questionnaire and St George's Respiratory Questionnaire. No adverse events were reported. The authors conclude that pulmonary rehabilitation is a highly effective and safe intervention for COPD patients post-exacerbation.This systematic review by Puhan et al. (2009) evaluates the effects of pulmonary rehabilitation on patients with Chronic Obstructive Pulmonary Disease (COPD) following an exacerbation. The review aimed to assess the impact on future hospital admissions, mortality, health-related quality of life, and exercise capacity. Six randomized controlled trials involving 219 patients were included. The results showed that pulmonary rehabilitation significantly reduced hospital admissions (pooled odds ratio 0.13, NNT 3) and mortality (pooled odds ratio 0.29, NNT 6) over the study periods. It also improved health-related quality of life and exercise capacity, with improvements in various domains of the Chronic Respiratory Questionnaire and St George's Respiratory Questionnaire. No adverse events were reported. The authors conclude that pulmonary rehabilitation is a highly effective and safe intervention for COPD patients post-exacerbation.