The article reviews the emerging functions of long non-coding RNAs (lncRNAs) in diverse cellular contexts. While lncRNAs were initially thought to play a minor role in gene regulation, recent studies have revealed their significant contributions. LncRNAs can regulate transcription through chromatin modulation, and they are involved in various post-transcriptional processes such as mRNA processing, stability, and translation. They also modulate protein activity and organize protein complexes. Additionally, lncRNAs can act as signaling molecules and contribute to genetic diversity through processes like recombination. The article highlights the versatility of RNA and its potential to serve multiple functions in the cell, emphasizing the need for more functional characterization methods to fully understand the roles of lncRNAs.The article reviews the emerging functions of long non-coding RNAs (lncRNAs) in diverse cellular contexts. While lncRNAs were initially thought to play a minor role in gene regulation, recent studies have revealed their significant contributions. LncRNAs can regulate transcription through chromatin modulation, and they are involved in various post-transcriptional processes such as mRNA processing, stability, and translation. They also modulate protein activity and organize protein complexes. Additionally, lncRNAs can act as signaling molecules and contribute to genetic diversity through processes like recombination. The article highlights the versatility of RNA and its potential to serve multiple functions in the cell, emphasizing the need for more functional characterization methods to fully understand the roles of lncRNAs.