Racial and ethnic disparities in the use of general anesthesia for cesarean delivery persist, with Black and Hispanic patients more likely to receive general anesthesia compared to non-Hispanic White patients. This study analyzed data from 35,117 patients who underwent cesarean delivery at Northwestern Medicine's Prentice Women's Hospital between 2007 and 2018. General anesthesia was used in 3.3% of cases, with rates varying by race and ethnicity. However, among patients with an epidural catheter in situ during labor, there were no significant racial or ethnic differences in general anesthesia use. The study found that the use of neuraxial labor analgesia may help reduce disparities in general anesthesia use. Disparities in general anesthesia use were associated with factors such as public insurance, multiple pregnancies, and preeclampsia. Black patients had higher odds of undergoing general anesthesia compared to White patients. The study highlights the need to address systemic and social factors contributing to these disparities. Future research should focus on understanding the causes of these disparities and developing strategies to eliminate them. The findings suggest that providing neuraxial labor analgesia can mitigate racial and ethnic disparities in general anesthesia use for cesarean delivery.Racial and ethnic disparities in the use of general anesthesia for cesarean delivery persist, with Black and Hispanic patients more likely to receive general anesthesia compared to non-Hispanic White patients. This study analyzed data from 35,117 patients who underwent cesarean delivery at Northwestern Medicine's Prentice Women's Hospital between 2007 and 2018. General anesthesia was used in 3.3% of cases, with rates varying by race and ethnicity. However, among patients with an epidural catheter in situ during labor, there were no significant racial or ethnic differences in general anesthesia use. The study found that the use of neuraxial labor analgesia may help reduce disparities in general anesthesia use. Disparities in general anesthesia use were associated with factors such as public insurance, multiple pregnancies, and preeclampsia. Black patients had higher odds of undergoing general anesthesia compared to White patients. The study highlights the need to address systemic and social factors contributing to these disparities. Future research should focus on understanding the causes of these disparities and developing strategies to eliminate them. The findings suggest that providing neuraxial labor analgesia can mitigate racial and ethnic disparities in general anesthesia use for cesarean delivery.