The letter to the editor raises concerns about the ethical standards of a randomized, placebo-controlled trial published by Kamyabi et al. The author notes that the authors did not provide any statement confirming informed consent was obtained from patients, particularly those in the placebo arm who did not receive any pain relief intervention. The letter also questions whether the study was reviewed and approved by an independent institutional review board. The author suggests that including such statements with each publication would enhance the credibility and ethical standards of the Annals and alert trainees and young practitioners to the importance of ethical principles in medical research, as outlined in the Declaration of Helsinki.The letter to the editor raises concerns about the ethical standards of a randomized, placebo-controlled trial published by Kamyabi et al. The author notes that the authors did not provide any statement confirming informed consent was obtained from patients, particularly those in the placebo arm who did not receive any pain relief intervention. The letter also questions whether the study was reviewed and approved by an independent institutional review board. The author suggests that including such statements with each publication would enhance the credibility and ethical standards of the Annals and alert trainees and young practitioners to the importance of ethical principles in medical research, as outlined in the Declaration of Helsinki.