Randomized, placebo-controlled trial

Randomized, placebo-controlled trial

March-April 2004 | Abdulmajeed Al Abdulkareem, MD, FRCSC
The author of the letter writes to the editor of the Annals, expressing concern about a recently published randomized, placebo-controlled trial by Kamyabi et al. The author notes that the study did not mention obtaining informed consent from participants, which is especially important in a placebo arm where patients receive no pain relief. The author also points out that the study did not mention approval by an independent institutional review board. The author highlights that the Annals requires such information in its "information for authors" section and believes the editorial board does not approve manuscripts without these statements. The author suggests including these statements with each publication to strengthen the credibility and ethical standards of the journal. The author also believes that including these statements will inform trainees and young practitioners about ethical principles in medical research involving human subjects, as outlined in the Declaration of Helsinki. The author requests that the journal include these statements with each publication. The letter is signed by Abdulmajeed Al Abdukareem, MD, FRCSC, from King Abdulaziz Medical City, Saudi Arabia.The author of the letter writes to the editor of the Annals, expressing concern about a recently published randomized, placebo-controlled trial by Kamyabi et al. The author notes that the study did not mention obtaining informed consent from participants, which is especially important in a placebo arm where patients receive no pain relief. The author also points out that the study did not mention approval by an independent institutional review board. The author highlights that the Annals requires such information in its "information for authors" section and believes the editorial board does not approve manuscripts without these statements. The author suggests including these statements with each publication to strengthen the credibility and ethical standards of the journal. The author also believes that including these statements will inform trainees and young practitioners about ethical principles in medical research involving human subjects, as outlined in the Declaration of Helsinki. The author requests that the journal include these statements with each publication. The letter is signed by Abdulmajeed Al Abdukareem, MD, FRCSC, from King Abdulaziz Medical City, Saudi Arabia.
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