The article "Rational Design of Organic Electrocatalysts for Hydrogen and Oxygen Electrocatalytic Applications" by Ruiqi Cheng et al. highlights the importance of efficient electrocatalysts in advancing green energy conversion technologies. Organic electrocatalysts, as cost-effective alternatives to noble metals, have gained attention due to their potential to enhance the performance of devices like metal-air batteries, proton/anion exchange membrane fuel cells, and water electrolyzers. However, the relationship between their properties and electrocatalytic activities remains unclear. The review emphasizes the need to understand the structure-activity relationship and design suitable electrode structures to leverage the unique features of organic electrocatalysts. Organic electrocatalysts are classified into four groups: small molecules, oligomers, polymers, and frameworks. Each group has specific structural and physicochemical properties that influence their electrocatalytic activities. The article discusses five strategies to enhance charge efficiency, mass transfer, and long-term stability during electrocatalytic reactions: integrated structures, surface property modulation, membrane technologies, electrolyte affinity regulation, and addition of anticorrosion species. The review provides a comprehensive overview of the current state of organic electrocatalysts and their practical applications, bridging the understanding gap and paving the way for future developments in green energy conversion technologies. It also highlights the advantages of organic electrocatalysts, such as their environmental friendliness, recyclability, and sustainability, and the challenges in applying them to real-world devices. The article concludes by systematically outlining the concepts and setup factors related to electrocatalytic reactions of organic compound-based materials and providing guidance for the development of low-cost, organic compound-based electrocatalysts for green energy use.The article "Rational Design of Organic Electrocatalysts for Hydrogen and Oxygen Electrocatalytic Applications" by Ruiqi Cheng et al. highlights the importance of efficient electrocatalysts in advancing green energy conversion technologies. Organic electrocatalysts, as cost-effective alternatives to noble metals, have gained attention due to their potential to enhance the performance of devices like metal-air batteries, proton/anion exchange membrane fuel cells, and water electrolyzers. However, the relationship between their properties and electrocatalytic activities remains unclear. The review emphasizes the need to understand the structure-activity relationship and design suitable electrode structures to leverage the unique features of organic electrocatalysts. Organic electrocatalysts are classified into four groups: small molecules, oligomers, polymers, and frameworks. Each group has specific structural and physicochemical properties that influence their electrocatalytic activities. The article discusses five strategies to enhance charge efficiency, mass transfer, and long-term stability during electrocatalytic reactions: integrated structures, surface property modulation, membrane technologies, electrolyte affinity regulation, and addition of anticorrosion species. The review provides a comprehensive overview of the current state of organic electrocatalysts and their practical applications, bridging the understanding gap and paving the way for future developments in green energy conversion technologies. It also highlights the advantages of organic electrocatalysts, such as their environmental friendliness, recyclability, and sustainability, and the challenges in applying them to real-world devices. The article concludes by systematically outlining the concepts and setup factors related to electrocatalytic reactions of organic compound-based materials and providing guidance for the development of low-cost, organic compound-based electrocatalysts for green energy use.