Recent Advances in Diagnosis and Treatment Approaches in Fungal Keratitis: A Narrative Review

Recent Advances in Diagnosis and Treatment Approaches in Fungal Keratitis: A Narrative Review

2024 | Laura Andreea Ghenciu, Alexandra Corina Faur, Sorin Lucian Bolintineanu, Madalina Casiana Salavat, Anca Laura Maghiari
Fungal keratitis is a severe corneal infection that can lead to significant visual impairment and financial burden. Recent advances in diagnosis and treatment have improved outcomes, emphasizing the importance of early and accurate diagnosis. Novel diagnostic methods include PCR-based approaches, metagenomic deep sequencing, in vivo confocal microscopy, and antifungal susceptibility testing. Early therapy is crucial for preserving visual acuity and minimizing corneal damage. Combination therapy is often more effective than monotherapy. Understanding the pathogenesis, early diagnosis, and prevention strategies is essential. This narrative review discusses recent progress in the diagnosis, treatment, and prevention of fungal keratitis, highlighting the importance of a multidisciplinary approach.Fungal keratitis is a severe corneal infection that can lead to significant visual impairment and financial burden. Recent advances in diagnosis and treatment have improved outcomes, emphasizing the importance of early and accurate diagnosis. Novel diagnostic methods include PCR-based approaches, metagenomic deep sequencing, in vivo confocal microscopy, and antifungal susceptibility testing. Early therapy is crucial for preserving visual acuity and minimizing corneal damage. Combination therapy is often more effective than monotherapy. Understanding the pathogenesis, early diagnosis, and prevention strategies is essential. This narrative review discusses recent progress in the diagnosis, treatment, and prevention of fungal keratitis, highlighting the importance of a multidisciplinary approach.
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