Recent Advances in Wearable Healthcare Devices: From Material to Application Wearable healthcare devices have revolutionized personal health monitoring and management by enabling continuous tracking of health indicators such as heart rate and blood glucose levels. These devices, ranging from fitness trackers to advanced biosensors, offer insights into human health, promoting proactive healthcare. This review discusses the fabrication methods of flexible wearable healthcare devices and their applications in medical care, along with potential challenges and future prospects. Wearable sensors are categorized into physical and chemical sensors. Physical sensors measure quantities like strain, pressure, and acceleration, while chemical sensors detect biochemical markers. Flexible substrates such as polydimethylsiloxane (PDMS), polyimide (PI), and polyurethane (PU) are commonly used due to their flexibility, biocompatibility, and durability. Recent advancements include self-healing materials and biodegradable polymers, which enhance the performance and sustainability of wearable devices. Materials like elastomers, thermosetting polymers, thermoplastic polymers, liquid crystalline polymers, polymer gels, intrinsic conducting polymers, and piezoelectric polymers are used in wearable sensors. These materials offer flexibility, conductivity, and sensitivity, enabling accurate monitoring of physiological signals. Biodegradable materials, such as polylactic acid (PLA) and polycaprolactone (PCL), are also gaining attention for their environmental benefits and biocompatibility. Applications of wearable devices include real-time monitoring of vital signs, gait analysis, and disease detection. First-generation devices, based on physical mechanisms, monitor parameters like heart rate and blood pressure. Second-generation devices use biochemical markers from body fluids such as saliva, sweat, and interstitial fluid (ISF) for non-invasive health monitoring. These devices leverage advanced materials and technologies to detect biomarkers, enabling early disease detection and personalized treatment. The integration of flexible electronics, self-healing materials, and biodegradable components is crucial for the development of next-generation wearable devices. These innovations enhance the functionality, comfort, and sustainability of wearable healthcare devices, paving the way for more effective and accessible healthcare solutions.Recent Advances in Wearable Healthcare Devices: From Material to Application Wearable healthcare devices have revolutionized personal health monitoring and management by enabling continuous tracking of health indicators such as heart rate and blood glucose levels. These devices, ranging from fitness trackers to advanced biosensors, offer insights into human health, promoting proactive healthcare. This review discusses the fabrication methods of flexible wearable healthcare devices and their applications in medical care, along with potential challenges and future prospects. Wearable sensors are categorized into physical and chemical sensors. Physical sensors measure quantities like strain, pressure, and acceleration, while chemical sensors detect biochemical markers. Flexible substrates such as polydimethylsiloxane (PDMS), polyimide (PI), and polyurethane (PU) are commonly used due to their flexibility, biocompatibility, and durability. Recent advancements include self-healing materials and biodegradable polymers, which enhance the performance and sustainability of wearable devices. Materials like elastomers, thermosetting polymers, thermoplastic polymers, liquid crystalline polymers, polymer gels, intrinsic conducting polymers, and piezoelectric polymers are used in wearable sensors. These materials offer flexibility, conductivity, and sensitivity, enabling accurate monitoring of physiological signals. Biodegradable materials, such as polylactic acid (PLA) and polycaprolactone (PCL), are also gaining attention for their environmental benefits and biocompatibility. Applications of wearable devices include real-time monitoring of vital signs, gait analysis, and disease detection. First-generation devices, based on physical mechanisms, monitor parameters like heart rate and blood pressure. Second-generation devices use biochemical markers from body fluids such as saliva, sweat, and interstitial fluid (ISF) for non-invasive health monitoring. These devices leverage advanced materials and technologies to detect biomarkers, enabling early disease detection and personalized treatment. The integration of flexible electronics, self-healing materials, and biodegradable components is crucial for the development of next-generation wearable devices. These innovations enhance the functionality, comfort, and sustainability of wearable healthcare devices, paving the way for more effective and accessible healthcare solutions.