This review summarizes recent advances in 3D printing of biomaterials, focusing on the development of complex biomedical devices for tissue engineering and regenerative medicine. 3D printing, initially used for pre-surgical models and tooling, has evolved to create custom implants, scaffolds, and diagnostic platforms. The review highlights the major advancements in materials and technologies for five common 3D printing techniques: Three Dimensional Printing (3DP), Fused Deposition Modeling (FDM), Selective Laser Sintering (SLS), Stereolithography (SLA), and 3D Plotting/Direct-Write/Bioprinting. Each technology's progress in tissue engineering is illustrated, along with key limitations that motivate further research. The review emphasizes the potential of 3D printing for personalized regenerative medicine, particularly in creating complex, patient-specific devices. The review also discusses the challenges of biomaterial selection and 3D shape specificity, and the need for further advancements in materials and technologies to overcome these limitations. The review concludes with a discussion of future directions for 3D printing in biomaterials, including the need for higher resolution and improved resolution of complex structures.This review summarizes recent advances in 3D printing of biomaterials, focusing on the development of complex biomedical devices for tissue engineering and regenerative medicine. 3D printing, initially used for pre-surgical models and tooling, has evolved to create custom implants, scaffolds, and diagnostic platforms. The review highlights the major advancements in materials and technologies for five common 3D printing techniques: Three Dimensional Printing (3DP), Fused Deposition Modeling (FDM), Selective Laser Sintering (SLS), Stereolithography (SLA), and 3D Plotting/Direct-Write/Bioprinting. Each technology's progress in tissue engineering is illustrated, along with key limitations that motivate further research. The review emphasizes the potential of 3D printing for personalized regenerative medicine, particularly in creating complex, patient-specific devices. The review also discusses the challenges of biomaterial selection and 3D shape specificity, and the need for further advancements in materials and technologies to overcome these limitations. The review concludes with a discussion of future directions for 3D printing in biomaterials, including the need for higher resolution and improved resolution of complex structures.