This review article provides a comprehensive overview of recent advances in multimodal tactile sensing integration and decoupling strategies. It highlights the significance of soft electronics in health monitoring and artificial sensation, emphasizing the need for efficient and multifunctional sensing devices. The authors discuss various sensing mechanisms, including pressure, strain, temperature, and humidity, and explore integration design principles, signal-decoupling strategies, and current applications. They also address the challenges and future perspectives in the field, aiming to inspire the development of next-generation soft multifunctional sensing devices. Key topics include the integration of monomodal sensors, multifunctional materials, multiple mechanism integration, and signal decoupling methods. The article concludes with a detailed discussion on the integration of individual sensing units, strain deformation suppression, multifunctional materials, and mechanism integration for multimodal sensing, as well as signal decoupling strategies to enhance the performance of multimodal tactile perception devices.This review article provides a comprehensive overview of recent advances in multimodal tactile sensing integration and decoupling strategies. It highlights the significance of soft electronics in health monitoring and artificial sensation, emphasizing the need for efficient and multifunctional sensing devices. The authors discuss various sensing mechanisms, including pressure, strain, temperature, and humidity, and explore integration design principles, signal-decoupling strategies, and current applications. They also address the challenges and future perspectives in the field, aiming to inspire the development of next-generation soft multifunctional sensing devices. Key topics include the integration of monomodal sensors, multifunctional materials, multiple mechanism integration, and signal decoupling methods. The article concludes with a detailed discussion on the integration of individual sensing units, strain deformation suppression, multifunctional materials, and mechanism integration for multimodal sensing, as well as signal decoupling strategies to enhance the performance of multimodal tactile perception devices.