Electrospun nanofibers have shown great potential in the development of advanced burn dressings due to their large specific surface area, high porosity, and similarity to the natural extracellular matrix (ECM). These nanofibers can load drugs and accelerate wound healing, offering a promising solution for burn treatment. This review discusses the concept of burns, types of electrospun nanofibers, polymers used in dressings, and drugs loaded into them. It also proposes promising aspects for commercial electrospun burn dressings. Burns are injuries to the skin caused by high temperatures, electricity, chemicals, friction, or radiation. They are classified into four levels based on severity. Burn healing involves four stages: hemostasis, inflammation, proliferation, and remodeling. Severe burns can lead to systemic infections, shock, and multiple organ failure. Traditional dressings have limitations in terms of function and side effects, making electrospun nanofibers a promising alternative. Electrospinning is a technique that allows the preparation of nanofibers with diameters ranging from nanometers to micrometers. It is cost-effective and efficient, enabling the creation of nanofibers with controlled structures and drug-loading capabilities. Electrospun nanofibers have a large surface area, high porosity, and can provide a moist environment for wound healing. They also have good biocompatibility and degradability, making them suitable for wound dressings. Various types of electrospun nanofibers, such as single-fluid, double-fluid, and multi-fluid electrospun nanofibers, have been developed. These nanofibers can be used to load drugs, including plant extracts, small molecule drugs, and nanoparticles, to enhance their therapeutic effects. Natural polymers like chitosan, gelatin, silk fibroin, and sodium alginate, as well as synthetic polymers like poly(ε-caprolactone), poly(vinyl alcohol), poly(ethylene oxide), poly(vinyl pyrrolidone), and polyurethane, are commonly used in electrospun nanofiber dressings. Drugs loaded into electrospun nanofiber dressings include curcumin, ginsenoside Rg1, kiwi extract, and bromelain, which have anti-inflammatory, antibacterial, and antioxidant properties. These drugs can accelerate wound healing, prevent scar formation, and reduce inflammation. The combination of these drugs with electrospun nanofibers can provide a synergistic effect, enhancing the therapeutic outcomes for burn treatment. The development of electrospun nanofiber dressings is a promising area in biomedical applications, with ongoing research aimed at improving their performance and commercial viability. These dressings offer advantages over traditional dressings, including better wound healing, reduced infection risk, and improved patient outcomes. The integration of various drugs and polymers into electrospun nanofibers isElectrospun nanofibers have shown great potential in the development of advanced burn dressings due to their large specific surface area, high porosity, and similarity to the natural extracellular matrix (ECM). These nanofibers can load drugs and accelerate wound healing, offering a promising solution for burn treatment. This review discusses the concept of burns, types of electrospun nanofibers, polymers used in dressings, and drugs loaded into them. It also proposes promising aspects for commercial electrospun burn dressings. Burns are injuries to the skin caused by high temperatures, electricity, chemicals, friction, or radiation. They are classified into four levels based on severity. Burn healing involves four stages: hemostasis, inflammation, proliferation, and remodeling. Severe burns can lead to systemic infections, shock, and multiple organ failure. Traditional dressings have limitations in terms of function and side effects, making electrospun nanofibers a promising alternative. Electrospinning is a technique that allows the preparation of nanofibers with diameters ranging from nanometers to micrometers. It is cost-effective and efficient, enabling the creation of nanofibers with controlled structures and drug-loading capabilities. Electrospun nanofibers have a large surface area, high porosity, and can provide a moist environment for wound healing. They also have good biocompatibility and degradability, making them suitable for wound dressings. Various types of electrospun nanofibers, such as single-fluid, double-fluid, and multi-fluid electrospun nanofibers, have been developed. These nanofibers can be used to load drugs, including plant extracts, small molecule drugs, and nanoparticles, to enhance their therapeutic effects. Natural polymers like chitosan, gelatin, silk fibroin, and sodium alginate, as well as synthetic polymers like poly(ε-caprolactone), poly(vinyl alcohol), poly(ethylene oxide), poly(vinyl pyrrolidone), and polyurethane, are commonly used in electrospun nanofiber dressings. Drugs loaded into electrospun nanofiber dressings include curcumin, ginsenoside Rg1, kiwi extract, and bromelain, which have anti-inflammatory, antibacterial, and antioxidant properties. These drugs can accelerate wound healing, prevent scar formation, and reduce inflammation. The combination of these drugs with electrospun nanofibers can provide a synergistic effect, enhancing the therapeutic outcomes for burn treatment. The development of electrospun nanofiber dressings is a promising area in biomedical applications, with ongoing research aimed at improving their performance and commercial viability. These dressings offer advantages over traditional dressings, including better wound healing, reduced infection risk, and improved patient outcomes. The integration of various drugs and polymers into electrospun nanofibers is