The article "Remote Control of Energy Transformation-Based Cancer Imaging and Therapy" by Hai Xu et al. discusses the use of exogenous remote stimuli, such as ultrasound, magnetic fields, light, and radiation, to enable precise and targeted cancer imaging and therapy. The authors highlight the importance of transforming these remote stimuli into different types of energy, such as mechanical, thermal, chemical, and radiative energy, to enhance the effectiveness of cancer treatments. The review covers various nanomedicines that can be activated by these transformed energies, including sonodynamic therapy (SDT), magnetic mechanical therapy (MMT), magnetic hyperthermia (MHT), and radiation therapy (RT). It also explores multimodal energy transformations, where multiple types of energy are combined to achieve synergistic therapeutic effects. The article emphasizes the advantages of these methods, such as deep tissue penetration, targeted activation, and reduced side effects, and provides examples of recent advancements in the field. Additionally, it discusses the integration of imaging techniques, such as ultrasound imaging (USI) and magnetic resonance imaging (MRI), to guide cancer treatments and improve diagnostic accuracy. The review concludes by highlighting the potential of these energy transformation-based approaches in cancer imaging and therapy, emphasizing their role in developing more precise and efficient cancer treatments.The article "Remote Control of Energy Transformation-Based Cancer Imaging and Therapy" by Hai Xu et al. discusses the use of exogenous remote stimuli, such as ultrasound, magnetic fields, light, and radiation, to enable precise and targeted cancer imaging and therapy. The authors highlight the importance of transforming these remote stimuli into different types of energy, such as mechanical, thermal, chemical, and radiative energy, to enhance the effectiveness of cancer treatments. The review covers various nanomedicines that can be activated by these transformed energies, including sonodynamic therapy (SDT), magnetic mechanical therapy (MMT), magnetic hyperthermia (MHT), and radiation therapy (RT). It also explores multimodal energy transformations, where multiple types of energy are combined to achieve synergistic therapeutic effects. The article emphasizes the advantages of these methods, such as deep tissue penetration, targeted activation, and reduced side effects, and provides examples of recent advancements in the field. Additionally, it discusses the integration of imaging techniques, such as ultrasound imaging (USI) and magnetic resonance imaging (MRI), to guide cancer treatments and improve diagnostic accuracy. The review concludes by highlighting the potential of these energy transformation-based approaches in cancer imaging and therapy, emphasizing their role in developing more precise and efficient cancer treatments.