Improving Bioscience Research Reporting: The ARRIVE Guidelines for Reporting Animal Research

Improving Bioscience Research Reporting: The ARRIVE Guidelines for Reporting Animal Research

June 2010 | Volume 8 | Issue 6 | e1000412 | Carol Kilkenny1*, William J. Browne2, Innes C. Cuthill3, Michael Emerson4, Douglas G. Altman5
The article discusses the importance of improving the reporting of bioscience research, particularly animal research, to enhance the quality and transparency of scientific publications. It highlights that inadequate reporting can lead to incomplete information, which is detrimental to scientific, ethical, and economic outcomes. The authors emphasize the need for detailed reporting of research methods and results to facilitate peer review, inform future research, and ensure reproducibility. They introduce the ARRIVE (Animals in Research: Reporting In Vivo Experiments) guidelines, which are based on the CONSORT Statement for clinical trials. These guidelines aim to provide a checklist of essential information, such as the number and characteristics of animals used, housing conditions, and experimental methods, to ensure comprehensive and high-quality reporting. The development of these guidelines involved consensus and consultation with experts from various fields, and they are intended to be applied to all areas of bioscience research using laboratory animals. The authors argue that improved reporting will maximize the output of published research and contribute to better scientific practices.The article discusses the importance of improving the reporting of bioscience research, particularly animal research, to enhance the quality and transparency of scientific publications. It highlights that inadequate reporting can lead to incomplete information, which is detrimental to scientific, ethical, and economic outcomes. The authors emphasize the need for detailed reporting of research methods and results to facilitate peer review, inform future research, and ensure reproducibility. They introduce the ARRIVE (Animals in Research: Reporting In Vivo Experiments) guidelines, which are based on the CONSORT Statement for clinical trials. These guidelines aim to provide a checklist of essential information, such as the number and characteristics of animals used, housing conditions, and experimental methods, to ensure comprehensive and high-quality reporting. The development of these guidelines involved consensus and consultation with experts from various fields, and they are intended to be applied to all areas of bioscience research using laboratory animals. The authors argue that improved reporting will maximize the output of published research and contribute to better scientific practices.
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