The ARRIVE guidelines aim to improve the reporting of animal research in bioscience. The authors highlight that many biomedical research publications lack adequate reporting, leading to incomplete information and limiting their usefulness for policy or clinical decisions. A review of animal research found significant omissions in reporting study hypotheses, animal characteristics, and statistical methods. These issues are consistent with problems in clinical research. Good reporting is essential for peer review and future research, as it allows for accurate critique and replication of experiments. The CONSORT statement for clinical trials has improved reporting quality, and similar guidelines have been developed for other research areas. The ARRIVE guidelines, based on CONSORT, provide a checklist of 20 items to ensure comprehensive reporting of animal experiments, including animal numbers, species, housing, and statistical methods. The guidelines are not mandatory but are intended to promote high-quality, transparent reporting. They are developed through consensus and consultation with scientists, statisticians, journal editors, and funders. The ARRIVE guidelines will be published in leading bioscience journals and are supported by funding bodies. Improved reporting will maximize the utility of animal research and reduce unnecessary animal use. The guidelines are intended to help authors, editors, and reviewers ensure completeness and transparency in research publications.The ARRIVE guidelines aim to improve the reporting of animal research in bioscience. The authors highlight that many biomedical research publications lack adequate reporting, leading to incomplete information and limiting their usefulness for policy or clinical decisions. A review of animal research found significant omissions in reporting study hypotheses, animal characteristics, and statistical methods. These issues are consistent with problems in clinical research. Good reporting is essential for peer review and future research, as it allows for accurate critique and replication of experiments. The CONSORT statement for clinical trials has improved reporting quality, and similar guidelines have been developed for other research areas. The ARRIVE guidelines, based on CONSORT, provide a checklist of 20 items to ensure comprehensive reporting of animal experiments, including animal numbers, species, housing, and statistical methods. The guidelines are not mandatory but are intended to promote high-quality, transparent reporting. They are developed through consensus and consultation with scientists, statisticians, journal editors, and funders. The ARRIVE guidelines will be published in leading bioscience journals and are supported by funding bodies. Improved reporting will maximize the utility of animal research and reduce unnecessary animal use. The guidelines are intended to help authors, editors, and reviewers ensure completeness and transparency in research publications.