Reporting Results of Cancer Treatment

Reporting Results of Cancer Treatment

1981 | A. B. MILLER, MB, FRCP(C), B. HOOGSTRATEN, MD, M. STAQUET, MD, AND A. WINKLER, MD*
The article discusses the standardized reporting of results from cancer treatment, developed through meetings organized by the World Health Organization (WHO). The recommendations aim to standardize the recording of baseline patient and tumor data, treatment methods, toxicity grading, response assessment, recurrence, and disease-free intervals. Key points include: 1. **Minimum Data Requirements**: Patients' and tumors' characteristics must be recorded to ensure accurate evaluation of reported data. 2. **Patient Data**: Essential information includes patient name, address, identification number, age, medical history, performance status (using a 5-grade scale), and additional factors like nutritional status. 3. **Tumor Data**: Information on tumor site, measurability, histopathology, anatomical extent, and laboratory and radiologic data are crucial. 4. **Treatment Reporting**: Details on surgical, radiotherapy, chemotherapy, immunotherapy, and combined modality therapies should be provided, including specific methods, dosages, and schedules. 5. **Toxicity Reporting**: Acute and subacute toxicities are graded, and chronic and late toxicities are documented annually. 6. **Response Assessment**: Criteria for complete, partial, no change, and progressive responses are defined, with specific guidelines for bone metastases. 7. **Recurrence and Disease-Free Interval**: Dates of first recurrence, relapse, and disease-free intervals are recorded, with detailed classification and follow-up procedures. 8. **Reporting Results**: Results should be reported in terms of frequency and duration, with clear definitions of numerators and denominators to ensure accuracy and completeness. The recommendations are intended to facilitate international comparison and validation of cancer treatment outcomes.The article discusses the standardized reporting of results from cancer treatment, developed through meetings organized by the World Health Organization (WHO). The recommendations aim to standardize the recording of baseline patient and tumor data, treatment methods, toxicity grading, response assessment, recurrence, and disease-free intervals. Key points include: 1. **Minimum Data Requirements**: Patients' and tumors' characteristics must be recorded to ensure accurate evaluation of reported data. 2. **Patient Data**: Essential information includes patient name, address, identification number, age, medical history, performance status (using a 5-grade scale), and additional factors like nutritional status. 3. **Tumor Data**: Information on tumor site, measurability, histopathology, anatomical extent, and laboratory and radiologic data are crucial. 4. **Treatment Reporting**: Details on surgical, radiotherapy, chemotherapy, immunotherapy, and combined modality therapies should be provided, including specific methods, dosages, and schedules. 5. **Toxicity Reporting**: Acute and subacute toxicities are graded, and chronic and late toxicities are documented annually. 6. **Response Assessment**: Criteria for complete, partial, no change, and progressive responses are defined, with specific guidelines for bone metastases. 7. **Recurrence and Disease-Free Interval**: Dates of first recurrence, relapse, and disease-free intervals are recorded, with detailed classification and follow-up procedures. 8. **Reporting Results**: Results should be reported in terms of frequency and duration, with clear definitions of numerators and denominators to ensure accuracy and completeness. The recommendations are intended to facilitate international comparison and validation of cancer treatment outcomes.
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