This review discusses the research status and perspectives of MXene-based materials for aqueous zinc-ion batteries (AZIBs). AZIBs are considered promising for large-scale energy storage due to their high safety, abundant zinc resources, high theoretical specific capacity, and low redox potential. However, they face challenges such as low electron conductivity, slow ion migration, zinc dendrites, and side reactions. MXene-based materials, with superior conductivity, large polar surfaces, and abundant active sites, can serve as cathode materials, electrolyte additives, and anode protection layers to regulate AZIBs' redox reactions. Although various materials have been used to improve AZIBs' electrochemical performance, there is a lack of in-depth discussion on the regulation mechanism of MXene-based materials. This review elaborates on the research progress of MXene-based materials in AZIBs, including their application in cathode materials and inhibition of zinc dendrites. It also discusses future prospects and development directions of MXene-based materials that may improve AZIBs' performance. MXene, a two-dimensional material, has metallic conductivity, unique layered structure, hydrophilicity, and excellent chemical stability, making it promising for energy storage. However, strong van der Waals forces and hydrogen bonding interactions can cause re-stacking of MXene layers, limiting their surface activity and processability. MXene with abundant functional groups can act as a growth substrate to form composites, effectively inhibiting layer re-stacking and enhancing performance. This review summarizes recent advances and challenges of MXene-based materials in AZIBs, focusing on their application in improving cathode performance and inhibiting anode dendrites. It also discusses structural design of MXene in electrode materials and regulation mechanisms for battery performance. Finally, it prospects opportunities and future directions for MXene-based materials to improve AZIBs' performance.This review discusses the research status and perspectives of MXene-based materials for aqueous zinc-ion batteries (AZIBs). AZIBs are considered promising for large-scale energy storage due to their high safety, abundant zinc resources, high theoretical specific capacity, and low redox potential. However, they face challenges such as low electron conductivity, slow ion migration, zinc dendrites, and side reactions. MXene-based materials, with superior conductivity, large polar surfaces, and abundant active sites, can serve as cathode materials, electrolyte additives, and anode protection layers to regulate AZIBs' redox reactions. Although various materials have been used to improve AZIBs' electrochemical performance, there is a lack of in-depth discussion on the regulation mechanism of MXene-based materials. This review elaborates on the research progress of MXene-based materials in AZIBs, including their application in cathode materials and inhibition of zinc dendrites. It also discusses future prospects and development directions of MXene-based materials that may improve AZIBs' performance. MXene, a two-dimensional material, has metallic conductivity, unique layered structure, hydrophilicity, and excellent chemical stability, making it promising for energy storage. However, strong van der Waals forces and hydrogen bonding interactions can cause re-stacking of MXene layers, limiting their surface activity and processability. MXene with abundant functional groups can act as a growth substrate to form composites, effectively inhibiting layer re-stacking and enhancing performance. This review summarizes recent advances and challenges of MXene-based materials in AZIBs, focusing on their application in improving cathode performance and inhibiting anode dendrites. It also discusses structural design of MXene in electrode materials and regulation mechanisms for battery performance. Finally, it prospects opportunities and future directions for MXene-based materials to improve AZIBs' performance.