This paper explores the concept of resilience from an interdisciplinary perspective, addressing key questions in resilience research. The authors, including Dr. Steven Southwick and others, define resilience as the ability to adapt well in the face of adversity, trauma, or stress, emphasizing its complexity and context-dependent nature. Resilience is viewed as a dynamic process involving biological, psychological, social, and cultural factors that interact to support healthy functioning. The panelists agree that resilience is not a single trait but a multifaceted construct that varies across individuals, families, organizations, and cultures. The discussion highlights the importance of considering multiple levels of analysis when studying resilience, including genetic, epigenetic, developmental, demographic, cultural, economic, and social variables. Resilience is seen as a continuum, with individuals varying in their ability to adapt across different domains of life. The panelists also emphasize the role of social support, cultural values, and environmental factors in fostering resilience. Dr. George Bonanno defines resilience as a stable trajectory of healthy functioning after a traumatic event, noting that it is not simply the absence of psychopathology but a pattern of adaptation. Dr. Rachel Yehuda suggests that resilience may co-occur with PTSD, emphasizing the importance of reintegration and positive adaptation. Dr. Ann Masten describes resilience as the capacity of a dynamic system to adapt successfully to disturbances, highlighting the role of multiple interacting systems in resilience. Dr. Catherine Panter-Brick emphasizes the cultural perspective on resilience, noting the importance of hope and meaning-making in fostering resilience. The panelists also discuss the biological underpinnings of resilience, including the role of genetics, epigenetics, and neurobiology. They highlight the importance of understanding how biological changes contribute to resilience and recovery. The discussion also addresses the role of technology and new research methods in advancing the science of resilience, including the use of biomarkers to measure physiological stress and resilience. Overall, the paper underscores the complexity of resilience and the need for interdisciplinary approaches to understand and enhance it. It emphasizes the importance of considering multiple factors, including biological, psychological, social, and cultural influences, in defining and promoting resilience. The discussion highlights the potential for integrating resilience concepts into various fields, including medicine, mental health, and science, to foster a more holistic understanding of resilience and its role in promoting well-being.This paper explores the concept of resilience from an interdisciplinary perspective, addressing key questions in resilience research. The authors, including Dr. Steven Southwick and others, define resilience as the ability to adapt well in the face of adversity, trauma, or stress, emphasizing its complexity and context-dependent nature. Resilience is viewed as a dynamic process involving biological, psychological, social, and cultural factors that interact to support healthy functioning. The panelists agree that resilience is not a single trait but a multifaceted construct that varies across individuals, families, organizations, and cultures. The discussion highlights the importance of considering multiple levels of analysis when studying resilience, including genetic, epigenetic, developmental, demographic, cultural, economic, and social variables. Resilience is seen as a continuum, with individuals varying in their ability to adapt across different domains of life. The panelists also emphasize the role of social support, cultural values, and environmental factors in fostering resilience. Dr. George Bonanno defines resilience as a stable trajectory of healthy functioning after a traumatic event, noting that it is not simply the absence of psychopathology but a pattern of adaptation. Dr. Rachel Yehuda suggests that resilience may co-occur with PTSD, emphasizing the importance of reintegration and positive adaptation. Dr. Ann Masten describes resilience as the capacity of a dynamic system to adapt successfully to disturbances, highlighting the role of multiple interacting systems in resilience. Dr. Catherine Panter-Brick emphasizes the cultural perspective on resilience, noting the importance of hope and meaning-making in fostering resilience. The panelists also discuss the biological underpinnings of resilience, including the role of genetics, epigenetics, and neurobiology. They highlight the importance of understanding how biological changes contribute to resilience and recovery. The discussion also addresses the role of technology and new research methods in advancing the science of resilience, including the use of biomarkers to measure physiological stress and resilience. Overall, the paper underscores the complexity of resilience and the need for interdisciplinary approaches to understand and enhance it. It emphasizes the importance of considering multiple factors, including biological, psychological, social, and cultural influences, in defining and promoting resilience. The discussion highlights the potential for integrating resilience concepts into various fields, including medicine, mental health, and science, to foster a more holistic understanding of resilience and its role in promoting well-being.