This review article, authored by Fang Jiang, Liehua Deng, Liangqing Zhang, Yin Cai, Chi Wai Cheung, and Zhengyuan Xia, provides an overview of the clinical characteristics, symptoms, complications, and treatments of COVID-19 as of late February 2020. The authors summarize key studies published up to this date to guide frontline medical staff in managing the outbreak. The review highlights that the main clinical manifestations of COVID-19 include fever (90% or more), cough (around 75%), and dyspnea (up to 50%). A significant subset of patients also presents with gastrointestinal symptoms. The estimated case fatality rate is about 2%, primarily due to acute respiratory distress syndrome (ARDS), acute kidney injury (AKI), and myocardial injury. The article also discusses the transmission dynamics, protective measures, and current treatments for COVID-19, emphasizing the importance of early diagnosis, symptom management, and supportive care. The authors conclude that while travel history to epidemic areas is crucial for diagnosis, frontline medical staff should employ protective measures and follow subsequent reports as the situation rapidly evolves.This review article, authored by Fang Jiang, Liehua Deng, Liangqing Zhang, Yin Cai, Chi Wai Cheung, and Zhengyuan Xia, provides an overview of the clinical characteristics, symptoms, complications, and treatments of COVID-19 as of late February 2020. The authors summarize key studies published up to this date to guide frontline medical staff in managing the outbreak. The review highlights that the main clinical manifestations of COVID-19 include fever (90% or more), cough (around 75%), and dyspnea (up to 50%). A significant subset of patients also presents with gastrointestinal symptoms. The estimated case fatality rate is about 2%, primarily due to acute respiratory distress syndrome (ARDS), acute kidney injury (AKI), and myocardial injury. The article also discusses the transmission dynamics, protective measures, and current treatments for COVID-19, emphasizing the importance of early diagnosis, symptom management, and supportive care. The authors conclude that while travel history to epidemic areas is crucial for diagnosis, frontline medical staff should employ protective measures and follow subsequent reports as the situation rapidly evolves.